STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptxRBacterial regulatory helix-turn-helix , lysr family protein; Transcriptional activator of the toxA (exotoxin) and regA genes (312 aa)    
Predicted Functional Partners:
DR97_5771
Bacterial regulatory helix-turn-helix , lysr family protein; Belongs to the LysR transcriptional regulatory family
  
     0.693
DR97_673
Bacterial regulatory helix-turn-helix , lysr family protein; Belongs to the LysR transcriptional regulatory family
  
    0.560
DR97_4524
Bacterial regulatory helix-turn-helix , lysr family protein; Belongs to the LysR transcriptional regulatory family
  
    0.558
DR97_789
Lysr family transcriptional regulator, transcriptional activator for bauabcd operon; Belongs to the LysR transcriptional regulatory family
  
     0.494
catR
Lysr family transcriptional regulator, benzoate and cis,cis-muconate-responsive activator of ben and cat genes; Belongs to the LysR transcriptional regulatory family
  
     0.428
trpI
Bacterial regulatory helix-turn-helix , lysr family protein; Activates the expression of the trpBA genes, which encode the two tryptophan synthase subunits, and represses initiation at its own promoter. Acts by binding to two adjacent sites in the intergenic region. In the absence of the inducer indoleglycerol phosphate (InGP), TrpI binds to site I. In the presence of InGP, TrpI binds to site I and site II. Binding to site II is site I dependent. InGP strongly stimulates binding to site II and is required for maximal activation of trpBA
  
     0.419
oxyR
Lysr family transcriptional regulator, hydrogen peroxide-inducible genes activator; Belongs to the LysR transcriptional regulatory family
  
     0.417
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
Server load: low (16%) [HD]