STRINGSTRING
ligD protein (Pseudomonas aeruginosa) - STRING interaction network
"ligD" - ATP-dependent DNA ligase in Pseudomonas aeruginosa
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ligDATP-dependent DNA ligase; ligD_pol- DNA polymerase LigD, polymerase domain (292 aa)    
Predicted Functional Partners:
ku
Non-homologous end joining protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5’- and 3’- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD (293 aa)
 
   
  0.982
DR97_3317
Phosphoesterase; yfcE- phosphodiesterase, MJ0936 family protein (150 aa)
   
     
  0.924
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5’-phosphoryl and 3’-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily (794 aa)
           
  0.893
DR97_4949
Phosphodiesterase (102 aa)
           
  0.757
DR97_6290
Putative membrane protein; phospholipase_D-nuclease N-terminal family protein (71 aa)
 
          0.741
DR97_6269
Uncharacterized protein (312 aa)
 
          0.726
yhxC
annotation not available (286 aa)
 
          0.708
pncC_2
Nicotinamide-nucleotide amidohydrolase PncC; cinA_cterm- competence/damage-inducible CinA C-terminal domain protein; Belongs to the CinA family (172 aa)
 
          0.665
pslN
annotation not available (333 aa)
 
          0.642
DR97_6289
annotation not available (79 aa)
              0.587
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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