cobO protein (Pseudomonas aeruginosa) - STRING interaction network

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cobO

Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids (203 aa)

Predicted Functional Partners:

cobQ

0.999

cobP

0.998

cobD

0.997

cobS

0.996

cobC

0.992

cobT

0.961

DR97_662

0.960

metH

0.957

cbiT

0.954

bluB

0.939

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR97_662	bluB	DR97_662	DR97_661	Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family	bluB- 5,6-dimethylbenzimidazole synthase	0.996
DR97_662	cbiT	DR97_662	DR97_5034	Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family	cbiT- precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit	0.953
DR97_662	cobC	DR97_662	DR97_659	Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family	L_thr_O3P_dcar- threonine-phosphate decarboxylase	0.986
DR97_662	cobD	DR97_662	DR97_660	Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family	Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	0.997
DR97_662	cobO	DR97_662	DR97_663	Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family	Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	0.960
DR97_662	cobP	DR97_662	DR97_657	Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family	Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate; Belongs to the CobU/CobP family	0.987
DR97_662	cobQ	DR97_662	DR97_658	Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family	Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	0.999
DR97_662	cobS	DR97_662	DR97_653	Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family	Adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5’-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5’-phosphate; Belongs to the CobS family	0.983
DR97_662	cobT	DR97_662	DR97_656	Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5’-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	0.994
DR97_662	metH	DR97_662	DR97_34	Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family	metH- methionine synthase	0.618
bluB	DR97_662	DR97_661	DR97_662	bluB- 5,6-dimethylbenzimidazole synthase	Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family	0.996
bluB	cbiT	DR97_661	DR97_5034	bluB- 5,6-dimethylbenzimidazole synthase	cbiT- precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit	0.667
bluB	cobC	DR97_661	DR97_659	bluB- 5,6-dimethylbenzimidazole synthase	L_thr_O3P_dcar- threonine-phosphate decarboxylase	0.966
bluB	cobD	DR97_661	DR97_660	bluB- 5,6-dimethylbenzimidazole synthase	Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	0.978
bluB	cobO	DR97_661	DR97_663	bluB- 5,6-dimethylbenzimidazole synthase	Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	0.939
bluB	cobP	DR97_661	DR97_657	bluB- 5,6-dimethylbenzimidazole synthase	Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate; Belongs to the CobU/CobP family	0.966
bluB	cobQ	DR97_661	DR97_658	bluB- 5,6-dimethylbenzimidazole synthase	Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	0.993
bluB	cobS	DR97_661	DR97_653	bluB- 5,6-dimethylbenzimidazole synthase	Adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5’-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5’-phosphate; Belongs to the CobS family	0.945
bluB	cobT	DR97_661	DR97_656	bluB- 5,6-dimethylbenzimidazole synthase	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5’-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	0.999
cbiT	DR97_662	DR97_5034	DR97_662	cbiT- precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit	Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family	0.953

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