STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aprDAtp-binding cassette, subfamily c, bacterial exporter for protease/lipase; Involved in the secretion of alkaline protease (593 aa)    
Predicted Functional Partners:
aprE
Type i secretion membrane fusion , hlyd family protein; Involved in the secretion of alkaline protease
  
 0.997
aprF
Type i secretion outer membrane , tolc family protein; Involved in the secretion of alkaline protease
  
 0.995
aprA
Alkaline metalloproteinase precursor; Belongs to the peptidase M10B family
 
  
 0.982
AprX
Hypothetical protein; Uncharacterized protein
  
  
 0.978
inh
Alkaline proteinase inhibitor; Inhibitor of the alkaline protease. It forms a non-covalent bond with the protease and may prevent its autocatalytic cleavage in the periplasm (By similarity)
 
  
 0.867
hasE
type_I_hlyD: type I secretion membrane fusion , HlyD family protein
  
 0.840
hasD
Atp-binding cassette, subfamily c, bacterial exporter for protease/lipase; Alkaline protease secretion ATP-binding protein AprD; type_I_sec_PrtD: type I secretion system ATPase family protein
  
 
 
0.809
HasF
Alkaline protease secretion protein AprF; type_I_sec_TolC: type I secretion outer membrane , TolC family protein
   
 0.669
DR97_5970
type_I_hlyD: type I secretion membrane fusion , HlyD family protein
   
 0.541
hasA
annotation not available
  
  
 0.454
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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