STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AprXHypothetical protein; Uncharacterized protein (414 aa)    
Predicted Functional Partners:
aprD
Atp-binding cassette, subfamily c, bacterial exporter for protease/lipase; Involved in the secretion of alkaline protease
  
  
 0.978
aprF
Type i secretion outer membrane , tolc family protein; Involved in the secretion of alkaline protease
  
  
 0.961
aprE
Type i secretion membrane fusion , hlyd family protein; Involved in the secretion of alkaline protease
  
  
 0.956
aprA
Alkaline metalloproteinase precursor; Belongs to the peptidase M10B family
  
  
 0.910
inh
Alkaline proteinase inhibitor; Inhibitor of the alkaline protease. It forms a non-covalent bond with the protease and may prevent its autocatalytic cleavage in the periplasm (By similarity)
  
  
 0.618
hasA
annotation not available
   
  
 0.487
ssuE
Nad(p)h-dependent fmn reductase; FMN_reduc_SsuE: FMN reductase
      
 0.451
exsB
Type iii secretion system chaperone yscw; Involved in the synthesis of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells . Pilot protein that is required for the proper localization of the secretin PscC in the outer membrane . Necessary for full in vivo virulence
      
 0.406
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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