STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rab8ARab8A, RAB family GTPase. (205 aa)    
Predicted Functional Partners:
GDIC1
Rab GDP dissociation inhibitor; Belongs to the Rab GDI family.
   
 0.887
D1LIC
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
    
 0.831
Esi_0089_0097
Exocyst complex component 6.
    
 0.791
Esi_0022_0103
Uncharacterized protein.
    
 0.782
Esi_0018_0131
Uncharacterized protein.
    
 0.779
GGTase-II-beta
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.
    
 0.756
RabX2
Divergent RAB-like GTPase, N-terminal myristoylation predicted by ExPASy Myristoylator.
  
 
0.738
Esi_0547_0004
Uncharacterized protein.
    
 0.733
Esi_0128_0025
Exocyst subunit Exo70 family protein; Component of the exocyst complex.
    
 0.733
Esi_0054_0034
Uncharacterized protein.
    
 0.729
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.