STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0488_0013Protein-serine/threonine kinase. (413 aa)    
Predicted Functional Partners:
PDH-3
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.793
Pyruvate
Pyruvate dehydrogenase E1 component alpha subunit, mitochondrial (PDHE1-A).
   
 0.737
PDH-2
Pyruvate dehydrogenase.
   
 0.737
Esi_0358_0029
Branched chain alpha-keto acid dehydrogenase E1 beta subunit.
    
 0.698
Esi_0499_0007
Uncharacterized protein.
    
 0.698
Esi_0102_0069
Lipoyl-binding domain-containing protein.
    
 0.649
Esi_0163_0048
Dihydrolipoamide S-acetyltransferase.
    
 0.649
PDH
Pyruvate dehydrogenase E1 component subunit beta.
    
 0.649
Esi_0326_0032
Dihydrolipoamide acetyltransferase.
    
 0.649
Esi_0322_0031
Dihydrolipoamide acetyltransferase (Partial).
    
 0.649
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.