Esi_0000_0340 protein (Ectocarpus siliculosus)

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Esi_0000_0340

Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. (581 aa)

Predicted Functional Partners:

Esi_0081_0020

0.983

FMT

0.976

Esi_0264_0018

0.973

Esi_0147_0067

0.972

Esi_0094_0032

0.972

Esi_0231_0013

0.961

Esi_0031_0020

0.952

Esi_0069_0033

0.949

Esi_0116_0039

0.942

Esi_0292_0008

0.942

Your Current Organism:

Ectocarpus siliculosus

NCBI taxonomy Id: 2880
Other names: E. siliculosus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Esi_0000_0340	Esi_0031_0020	D8LBA4	D8LKS8	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	Probable bifunctional purine synthesis protein.	0.952
Esi_0000_0340	Esi_0069_0033	D8LBA4	D8LRL2	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	Pterin-binding domain-containing protein.	0.949
Esi_0000_0340	Esi_0081_0020	D8LBA4	D8LT70	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	ATP-grasp domain-containing protein.	0.983
Esi_0000_0340	Esi_0094_0032	D8LBA4	D7G905	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	Deoxyuridine 5'-triphosphate nucleotidohydrolase.	0.972
Esi_0000_0340	Esi_0116_0039	D8LBA4	D8LDA9	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	Uncharacterized protein.	0.942
Esi_0000_0340	Esi_0147_0067	D8LBA4	D7FKR9	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.972
Esi_0000_0340	Esi_0231_0013	D8LBA4	D7FSC0	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	Thymidylate_kin domain-containing protein.	0.961
Esi_0000_0340	Esi_0264_0018	D8LBA4	D8LJR7	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	CMP/dCMP-type deaminase domain-containing protein.	0.973
Esi_0000_0340	Esi_0292_0008	D8LBA4	D8LKA5	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	Uncharacterized protein.	0.942
Esi_0000_0340	FMT	D8LBA4	D8LKZ7	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	Methionyl-tRNA formyltransferase.	0.976
Esi_0031_0020	Esi_0000_0340	D8LKS8	D8LBA4	Probable bifunctional purine synthesis protein.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	0.952
Esi_0031_0020	Esi_0081_0020	D8LKS8	D8LT70	Probable bifunctional purine synthesis protein.	ATP-grasp domain-containing protein.	0.998
Esi_0031_0020	Esi_0116_0039	D8LKS8	D8LDA9	Probable bifunctional purine synthesis protein.	Uncharacterized protein.	0.936
Esi_0031_0020	Esi_0231_0013	D8LKS8	D7FSC0	Probable bifunctional purine synthesis protein.	Thymidylate_kin domain-containing protein.	0.427
Esi_0031_0020	Esi_0292_0008	D8LKS8	D8LKA5	Probable bifunctional purine synthesis protein.	Uncharacterized protein.	0.936
Esi_0031_0020	FMT	D8LKS8	D8LKZ7	Probable bifunctional purine synthesis protein.	Methionyl-tRNA formyltransferase.	0.769
Esi_0069_0033	Esi_0000_0340	D8LRL2	D8LBA4	Pterin-binding domain-containing protein.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	0.949
Esi_0069_0033	Esi_0081_0020	D8LRL2	D8LT70	Pterin-binding domain-containing protein.	ATP-grasp domain-containing protein.	0.790
Esi_0069_0033	Esi_0231_0013	D8LRL2	D7FSC0	Pterin-binding domain-containing protein.	Thymidylate_kin domain-containing protein.	0.765
Esi_0069_0033	FMT	D8LRL2	D8LKZ7	Pterin-binding domain-containing protein.	Methionyl-tRNA formyltransferase.	0.439

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