STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0000_0401Uncharacterized protein. (647 aa)    
Predicted Functional Partners:
CYP97F4
Cytochrome P450; Belongs to the cytochrome P450 family.
 
  
 0.946
Esi_0346_0011
Uncharacterized protein.
 
 0.919
CYP97E3
Cytochrome P450.
 
  
 0.918
Esi_0346_0014
Uncharacterized protein.
 0.915
Esi_0115_0055
Cytochrome b5 heme-binding domain-containing protein.
    
 0.900
Nia
NAD(P)H-Nitrate reductase.
    
 0.900
Esi_0003_0129
Ferredoxin nitrite reductase.
  
 0.864
Esi_0274_0036
Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...]
    
 0.811
Esi_0274_0029
Phosphoadenylyl-sulfate reductase (Thioredoxin).
  
 
 0.802
Esi_0302_0008
Similar to Cytochrome b5 reductase 4; Belongs to the cytochrome b5 family.
    
 0.790
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.