STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0126_0044DNA topoisomerase I (Partial). (1050 aa)    
Predicted Functional Partners:
Esi_0185_0042
DEAD box helicase similar to CG7922-PA.
   
 0.996
Esi_0114_0018
Similar to Werner syndrome protein.
  
 0.961
Esi_0124_0050
3'-5' exonuclease domain-containing protein.
  
 0.961
Esi_0029_0066
annotation not available
  
 0.961
Esi_0404_0005
3'-5' exonuclease domain-containing protein.
  
 0.961
Esi_0521_0008
3'-5' exonuclease domain-containing protein.
  
 0.961
Esi_0098_0023
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 0.961
Esi_0105_0023
ERCC4 domain-containing protein.
    
 0.871
Esi_0279_0024
Replication protein A subunit.
   
 0.826
Esi_0279_0025
Rep-A_N domain-containing protein.
   
 0.826
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.