STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0020_0103PPIase cyclophilin-type domain-containing protein. (454 aa)    
Predicted Functional Partners:
Cys-2
Cathepsin L-like proteinase; Belongs to the peptidase C1 family.
    
 
 0.896
RAN
GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
   
 0.756
Esi_0089_0051
Uncharacterized protein.
    
 0.734
Esi_0003_0340
PPIase cyclophilin-type domain-containing protein.
  
 
0.732
Esi_0032_0079
SKIP_SNW domain-containing protein.
    
 0.732
Esi_0042_0055
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 
0.732
Esi_0007_0219
Ran-GTPase activating protein.
   
 0.732
Esi_0015_0081
Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).
   
 0.730
Esi_0036_0078
Uncharacterized protein.
   
  0.717
Esi_0029_0113
Small ubiquitin-like modifier.
   
 0.706
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.