STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0095_0027ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (645 aa)    
Predicted Functional Partners:
Esi_0185_0042
DEAD box helicase similar to CG7922-PA.
   
 0.995
MRE11
Meiotic recombination 11.
  
 0.816
Esi_0021_0144
ATP-dependent RNA helicase, putative.
   
 0.802
Esi_0279_0024
Replication protein A subunit.
    
 0.790
Esi_0279_0025
Rep-A_N domain-containing protein.
    
 0.790
Esi_0105_0023
ERCC4 domain-containing protein.
    
 0.782
RAD52
DNA repair protein RAD52 homolog.
    
 0.780
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.780
Esi_0533_0015
ERCC4 domain containing protein.
   
 0.780
Esi_0006_0201
ERCC4 domain containing protein.
   
 0.780
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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