node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BBta_0092 | BBta_0334 | BBta_0092 | BBta_0334 | Putative ATP-dependent DNA ligase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Hypothetical protein; DNA topoisomerase I domain; Evidence: Similar to previously reported genes of unknown function. | 0.716 |
BBta_0092 | BBta_0799 | BBta_0092 | BBta_0799 | Putative ATP-dependent DNA ligase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Putative metallo-hydrolase/oxidoreductase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.605 |
BBta_0092 | BBta_5672 | BBta_0092 | BBta_5672 | Putative ATP-dependent DNA ligase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | 0.626 |
BBta_0092 | BBta_6235 | BBta_0092 | BBta_6235 | Putative ATP-dependent DNA ligase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Hypothetical protein; Evidence: Similar to previously reported genes of unknown function. | 0.633 |
BBta_0092 | BBta_7781 | BBta_0092 | BBta_7781 | Putative ATP-dependent DNA ligase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Putative DNA ligase-like protein; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | 0.932 |
BBta_0092 | dnaN | BBta_0092 | BBta_0002 | Putative ATP-dependent DNA ligase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.948 |
BBta_0092 | ku | BBta_0092 | BBta_3065 | Putative ATP-dependent DNA ligase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.820 |
BBta_0092 | ku-2 | BBta_0092 | BBta_3324 | Putative ATP-dependent DNA ligase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.823 |
BBta_0092 | ku-3 | BBta_0092 | BBta_6331 | Putative ATP-dependent DNA ligase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.818 |
BBta_0092 | polA | BBta_0092 | BBta_7357 | Putative ATP-dependent DNA ligase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.884 |
BBta_0334 | BBta_0092 | BBta_0334 | BBta_0092 | Hypothetical protein; DNA topoisomerase I domain; Evidence: Similar to previously reported genes of unknown function. | Putative ATP-dependent DNA ligase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | 0.716 |
BBta_0334 | BBta_0799 | BBta_0334 | BBta_0799 | Hypothetical protein; DNA topoisomerase I domain; Evidence: Similar to previously reported genes of unknown function. | Putative metallo-hydrolase/oxidoreductase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.485 |
BBta_0334 | BBta_7781 | BBta_0334 | BBta_7781 | Hypothetical protein; DNA topoisomerase I domain; Evidence: Similar to previously reported genes of unknown function. | Putative DNA ligase-like protein; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | 0.659 |
BBta_0334 | dnaN | BBta_0334 | BBta_0002 | Hypothetical protein; DNA topoisomerase I domain; Evidence: Similar to previously reported genes of unknown function. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.482 |
BBta_0334 | ku | BBta_0334 | BBta_3065 | Hypothetical protein; DNA topoisomerase I domain; Evidence: Similar to previously reported genes of unknown function. | Hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.670 |
BBta_0334 | ku-2 | BBta_0334 | BBta_3324 | Hypothetical protein; DNA topoisomerase I domain; Evidence: Similar to previously reported genes of unknown function. | Hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.672 |
BBta_0334 | ku-3 | BBta_0334 | BBta_6331 | Hypothetical protein; DNA topoisomerase I domain; Evidence: Similar to previously reported genes of unknown function. | Hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.666 |
BBta_0334 | polA | BBta_0334 | BBta_7357 | Hypothetical protein; DNA topoisomerase I domain; Evidence: Similar to previously reported genes of unknown function. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.490 |
BBta_0799 | BBta_0092 | BBta_0799 | BBta_0092 | Putative metallo-hydrolase/oxidoreductase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Putative ATP-dependent DNA ligase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | 0.605 |
BBta_0799 | BBta_0334 | BBta_0799 | BBta_0334 | Putative metallo-hydrolase/oxidoreductase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Hypothetical protein; DNA topoisomerase I domain; Evidence: Similar to previously reported genes of unknown function. | 0.485 |