STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phhBPterin-4-alpha-carbinolamine dehydratase; Evidence: Function of strongly homologous gene. (99 aa)    
Predicted Functional Partners:
hpd
4-hydroxyphenylpyruvate dioxygenase; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic.
  
  
 0.837
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
  
 0.720
fahA
Fumarylacetoacetate hydrolase; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic.
 
  
 0.717
BBta_0247
Hypothetical protein; Evidence: Similar to previously reported genes of unknown function.
       0.589
tyrB
Aminotransferase; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic; PUBMED: 10417420, 8809108.
  
  
 0.565
BBta_4224
Aminotransferase; Localization: 2 : Cytoplasmic; Evidence: Function of strongly homologous gene.
  
  
 0.565
BBta_6524
Maleylacetoacetate isomerase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; PUBMED: 10220173.
 
  
 0.524
maiA
Maleylacetoacetate isomerase; Localization: 2 : Cytoplasmic; Evidence: Function of homologous gene experimentally demonstrated in an other organism.
 
  
 0.510
BBta_6113
4-hydroxyphenylpyruvate dioxygenase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic.
  
  
 0.506
BBta_2270
Hypothetical protein; Evidence: Similar to previously reported genes of unknown function.
   
    0.432
Your Current Organism:
Bradyrhizobium sp. BTAi1
NCBI taxonomy Id: 288000
Other names: B. sp. BTAi1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.