node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BBta_0413 | ctpA | BBta_0413 | BBta_0414 | Hypothetical protein; Evidence: Similar to previously reported genes of unknown function. | C-terminal processing peptidase-3, Serine peptidase, MEROPS family S41A; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Belongs to the peptidase S41A family. | 0.517 |
BBta_0413 | nudH | BBta_0413 | BBta_0411 | Hypothetical protein; Evidence: Similar to previously reported genes of unknown function. | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.437 |
BBta_0413 | nudH-2 | BBta_0413 | BBta_0412 | Hypothetical protein; Evidence: Similar to previously reported genes of unknown function. | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.609 |
BBta_3974 | nnrD | BBta_3974 | BBta_4579 | Putative ATP-dependent RNA helicase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; Belongs to the DEAD box helicase family. | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] | 0.922 |
BBta_3974 | nudH | BBta_3974 | BBta_0411 | Putative ATP-dependent RNA helicase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; Belongs to the DEAD box helicase family. | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.512 |
BBta_3974 | nudH-2 | BBta_3974 | BBta_0412 | Putative ATP-dependent RNA helicase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; Belongs to the DEAD box helicase family. | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.512 |
BBta_3974 | rnr | BBta_3974 | BBta_4734 | Putative ATP-dependent RNA helicase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; Belongs to the DEAD box helicase family. | RNAse R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.496 |
BBta_3974 | rph | BBta_3974 | BBta_0186 | Putative ATP-dependent RNA helicase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; Belongs to the DEAD box helicase family. | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.553 |
BBta_4919 | nnrD | BBta_4919 | BBta_4579 | Putative DEAD-box cold-shock protein, ATP-independent RNA helicase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; Belongs to the DEAD box helicase family. | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] | 0.922 |
BBta_4919 | nudH | BBta_4919 | BBta_0411 | Putative DEAD-box cold-shock protein, ATP-independent RNA helicase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; Belongs to the DEAD box helicase family. | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.512 |
BBta_4919 | nudH-2 | BBta_4919 | BBta_0412 | Putative DEAD-box cold-shock protein, ATP-independent RNA helicase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; Belongs to the DEAD box helicase family. | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.512 |
BBta_4919 | rnr | BBta_4919 | BBta_4734 | Putative DEAD-box cold-shock protein, ATP-independent RNA helicase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; Belongs to the DEAD box helicase family. | RNAse R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.496 |
BBta_4919 | rph | BBta_4919 | BBta_0186 | Putative DEAD-box cold-shock protein, ATP-independent RNA helicase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; Belongs to the DEAD box helicase family. | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.553 |
BBta_7546 | nnrD | BBta_7546 | BBta_4579 | Putative ATP-dependent RNA and DNA helicase; Translation initiation factor 2; Evidence: Similar to previously reported genes of unknown function. | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] | 0.922 |
BBta_7546 | nudH | BBta_7546 | BBta_0411 | Putative ATP-dependent RNA and DNA helicase; Translation initiation factor 2; Evidence: Similar to previously reported genes of unknown function. | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.476 |
BBta_7546 | nudH-2 | BBta_7546 | BBta_0412 | Putative ATP-dependent RNA and DNA helicase; Translation initiation factor 2; Evidence: Similar to previously reported genes of unknown function. | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.576 |
BBta_7546 | rnr | BBta_7546 | BBta_4734 | Putative ATP-dependent RNA and DNA helicase; Translation initiation factor 2; Evidence: Similar to previously reported genes of unknown function. | RNAse R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.468 |
BBta_7546 | rph | BBta_7546 | BBta_0186 | Putative ATP-dependent RNA and DNA helicase; Translation initiation factor 2; Evidence: Similar to previously reported genes of unknown function. | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.553 |
ctpA | BBta_0413 | BBta_0414 | BBta_0413 | C-terminal processing peptidase-3, Serine peptidase, MEROPS family S41A; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Belongs to the peptidase S41A family. | Hypothetical protein; Evidence: Similar to previously reported genes of unknown function. | 0.517 |
ctpA | nudH | BBta_0414 | BBta_0411 | C-terminal processing peptidase-3, Serine peptidase, MEROPS family S41A; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Belongs to the peptidase S41A family. | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.458 |