node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BBta_3495 | BBta_4066 | BBta_3495 | BBta_4066 | NH(3)-dependent NAD(+) synthetase; (NadE-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; In the C-terminal section; belongs to the NAD synthetase family. | Competence-damage induced protein (CinA) domain; Evidence: Similar to previously reported genes of unknown function; Localization: 2 : Cytoplasmic; Belongs to the CinA family. | 0.537 |
BBta_3495 | cobB-3 | BBta_3495 | BBta_4037 | NH(3)-dependent NAD(+) synthetase; (NadE-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; In the C-terminal section; belongs to the NAD synthetase family. | Putative transciptional regulatory Sir2-family protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.939 |
BBta_3495 | nadC | BBta_3495 | BBta_4755 | NH(3)-dependent NAD(+) synthetase; (NadE-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; In the C-terminal section; belongs to the NAD synthetase family. | Nicotinate-nucleotide pyrophosphorylase (carboxylating); Evidence: Function of strongly homologous gene; Localization: 2 : Cytoplasmic; Belongs to the NadC/ModD family. | 0.505 |
BBta_3495 | nadD | BBta_3495 | BBta_0418 | NH(3)-dependent NAD(+) synthetase; (NadE-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; In the C-terminal section; belongs to the NAD synthetase family. | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.954 |
BBta_3495 | nadE | BBta_3495 | BBta_0979 | NH(3)-dependent NAD(+) synthetase; (NadE-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; In the C-terminal section; belongs to the NAD synthetase family. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.930 |
BBta_3495 | nadK | BBta_3495 | BBta_5177 | NH(3)-dependent NAD(+) synthetase; (NadE-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; In the C-terminal section; belongs to the NAD synthetase family. | Putative inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.947 |
BBta_3495 | pncB | BBta_3495 | BBta_0308 | NH(3)-dependent NAD(+) synthetase; (NadE-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; In the C-terminal section; belongs to the NAD synthetase family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.690 |
BBta_3495 | pntA2 | BBta_3495 | BBta_6857 | NH(3)-dependent NAD(+) synthetase; (NadE-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; In the C-terminal section; belongs to the NAD synthetase family. | Nicotinamide nucleotide transhydrogenase, subunit alpha2; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | 0.908 |
BBta_3495 | pntA2-2 | BBta_3495 | BBta_6858 | NH(3)-dependent NAD(+) synthetase; (NadE-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; In the C-terminal section; belongs to the NAD synthetase family. | Nicotinamide nucleotide transhydrogenase, subunit alpha1; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | 0.908 |
BBta_4066 | BBta_3495 | BBta_4066 | BBta_3495 | Competence-damage induced protein (CinA) domain; Evidence: Similar to previously reported genes of unknown function; Localization: 2 : Cytoplasmic; Belongs to the CinA family. | NH(3)-dependent NAD(+) synthetase; (NadE-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; In the C-terminal section; belongs to the NAD synthetase family. | 0.537 |
BBta_4066 | nadC | BBta_4066 | BBta_4755 | Competence-damage induced protein (CinA) domain; Evidence: Similar to previously reported genes of unknown function; Localization: 2 : Cytoplasmic; Belongs to the CinA family. | Nicotinate-nucleotide pyrophosphorylase (carboxylating); Evidence: Function of strongly homologous gene; Localization: 2 : Cytoplasmic; Belongs to the NadC/ModD family. | 0.915 |
BBta_4066 | nadD | BBta_4066 | BBta_0418 | Competence-damage induced protein (CinA) domain; Evidence: Similar to previously reported genes of unknown function; Localization: 2 : Cytoplasmic; Belongs to the CinA family. | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.943 |
BBta_4066 | nadE | BBta_4066 | BBta_0979 | Competence-damage induced protein (CinA) domain; Evidence: Similar to previously reported genes of unknown function; Localization: 2 : Cytoplasmic; Belongs to the CinA family. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.474 |
BBta_4066 | pncB | BBta_4066 | BBta_0308 | Competence-damage induced protein (CinA) domain; Evidence: Similar to previously reported genes of unknown function; Localization: 2 : Cytoplasmic; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.931 |
cobB-3 | BBta_3495 | BBta_4037 | BBta_3495 | Putative transciptional regulatory Sir2-family protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | NH(3)-dependent NAD(+) synthetase; (NadE-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; In the C-terminal section; belongs to the NAD synthetase family. | 0.939 |
cobB-3 | nadD | BBta_4037 | BBta_0418 | Putative transciptional regulatory Sir2-family protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.929 |
cobB-3 | nadE | BBta_4037 | BBta_0979 | Putative transciptional regulatory Sir2-family protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.939 |
cobB-3 | nadK | BBta_4037 | BBta_5177 | Putative transciptional regulatory Sir2-family protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | Putative inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.922 |
cobB-3 | pntA2 | BBta_4037 | BBta_6857 | Putative transciptional regulatory Sir2-family protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | Nicotinamide nucleotide transhydrogenase, subunit alpha2; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | 0.908 |
cobB-3 | pntA2-2 | BBta_4037 | BBta_6858 | Putative transciptional regulatory Sir2-family protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | Nicotinamide nucleotide transhydrogenase, subunit alpha1; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | 0.911 |