STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadDPutative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (192 aa)    
Predicted Functional Partners:
rsfS
Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
 0.963
nadE
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.954
BBta_3495
NH(3)-dependent NAD(+) synthetase; (NadE-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; In the C-terminal section; belongs to the NAD synthetase family.
  
 
 0.954
BBta_4066
Competence-damage induced protein (CinA) domain; Evidence: Similar to previously reported genes of unknown function; Localization: 2 : Cytoplasmic; Belongs to the CinA family.
  
 
 0.943
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
  
 
 0.942
nadC
Nicotinate-nucleotide pyrophosphorylase (carboxylating); Evidence: Function of strongly homologous gene; Localization: 2 : Cytoplasmic; Belongs to the NadC/ModD family.
 
  
 0.938
nadK
Putative inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.934
cobB-3
Putative transciptional regulatory Sir2-family protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
   
 0.929
pntA2
Nicotinamide nucleotide transhydrogenase, subunit alpha2; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein.
     
 0.909
pntA2-2
Nicotinamide nucleotide transhydrogenase, subunit alpha1; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein.
     
 0.909
Your Current Organism:
Bradyrhizobium sp. BTAi1
NCBI taxonomy Id: 288000
Other names: B. sp. BTAi1
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