node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BBta_0074 | BBta_2650 | BBta_0074 | BBta_2650 | Putative Molybdopterin biosynthesis protein moeB; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Hypothetical protein; NUDIX domain; Evidence: Similar to previously reported genes of unknown function; Belongs to the Nudix hydrolase family. | 0.742 |
BBta_0074 | thiC | BBta_0074 | BBta_6226 | Putative Molybdopterin biosynthesis protein moeB; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.886 |
BBta_0074 | thiD | BBta_0074 | BBta_5600 | Putative Molybdopterin biosynthesis protein moeB; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Phosphomethylpyrimidine kinase / hydroxymethylpyrimidine kinase; Evidence: Function of homologous gene experimentally demonstrated in an other organism. | 0.874 |
BBta_0074 | thiG | BBta_0074 | BBta_6224 | Putative Molybdopterin biosynthesis protein moeB; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.956 |
BBta_0074 | thiS | BBta_0074 | BBta_6223 | Putative Molybdopterin biosynthesis protein moeB; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Sulfur carrier protein ThiS; Evidence: Function of strongly homologous gene. | 0.969 |
BBta_2649 | BBta_2650 | BBta_2649 | BBta_2650 | Hypothetical protein; Evidence: Similar to previously reported genes of unknown function. | Hypothetical protein; NUDIX domain; Evidence: Similar to previously reported genes of unknown function; Belongs to the Nudix hydrolase family. | 0.830 |
BBta_2649 | BBta_2651 | BBta_2649 | BBta_2651 | Hypothetical protein; Evidence: Similar to previously reported genes of unknown function. | Putative NADH dehydrogenase; (NADH quinone oxidoreductase)(nuoL3-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 5 : Inner membrane protein. | 0.811 |
BBta_2649 | BBta_2652 | BBta_2649 | BBta_2652 | Hypothetical protein; Evidence: Similar to previously reported genes of unknown function. | Hypothetical protein; Evidence: Similar to previously reported genes of unknown function; Belongs to the UPF0753 family. | 0.846 |
BBta_2650 | BBta_0074 | BBta_2650 | BBta_0074 | Hypothetical protein; NUDIX domain; Evidence: Similar to previously reported genes of unknown function; Belongs to the Nudix hydrolase family. | Putative Molybdopterin biosynthesis protein moeB; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | 0.742 |
BBta_2650 | BBta_2649 | BBta_2650 | BBta_2649 | Hypothetical protein; NUDIX domain; Evidence: Similar to previously reported genes of unknown function; Belongs to the Nudix hydrolase family. | Hypothetical protein; Evidence: Similar to previously reported genes of unknown function. | 0.830 |
BBta_2650 | BBta_2651 | BBta_2650 | BBta_2651 | Hypothetical protein; NUDIX domain; Evidence: Similar to previously reported genes of unknown function; Belongs to the Nudix hydrolase family. | Putative NADH dehydrogenase; (NADH quinone oxidoreductase)(nuoL3-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 5 : Inner membrane protein. | 0.790 |
BBta_2650 | BBta_2652 | BBta_2650 | BBta_2652 | Hypothetical protein; NUDIX domain; Evidence: Similar to previously reported genes of unknown function; Belongs to the Nudix hydrolase family. | Hypothetical protein; Evidence: Similar to previously reported genes of unknown function; Belongs to the UPF0753 family. | 0.780 |
BBta_2650 | nnrD | BBta_2650 | BBta_4579 | Hypothetical protein; NUDIX domain; Evidence: Similar to previously reported genes of unknown function; Belongs to the Nudix hydrolase family. | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] | 0.899 |
BBta_2650 | rnr | BBta_2650 | BBta_4734 | Hypothetical protein; NUDIX domain; Evidence: Similar to previously reported genes of unknown function; Belongs to the Nudix hydrolase family. | RNAse R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.653 |
BBta_2650 | thiC | BBta_2650 | BBta_6226 | Hypothetical protein; NUDIX domain; Evidence: Similar to previously reported genes of unknown function; Belongs to the Nudix hydrolase family. | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.881 |
BBta_2650 | thiD | BBta_2650 | BBta_5600 | Hypothetical protein; NUDIX domain; Evidence: Similar to previously reported genes of unknown function; Belongs to the Nudix hydrolase family. | Phosphomethylpyrimidine kinase / hydroxymethylpyrimidine kinase; Evidence: Function of homologous gene experimentally demonstrated in an other organism. | 0.851 |
BBta_2650 | thiG | BBta_2650 | BBta_6224 | Hypothetical protein; NUDIX domain; Evidence: Similar to previously reported genes of unknown function; Belongs to the Nudix hydrolase family. | Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.839 |
BBta_2650 | thiS | BBta_2650 | BBta_6223 | Hypothetical protein; NUDIX domain; Evidence: Similar to previously reported genes of unknown function; Belongs to the Nudix hydrolase family. | Sulfur carrier protein ThiS; Evidence: Function of strongly homologous gene. | 0.825 |
BBta_2651 | BBta_2649 | BBta_2651 | BBta_2649 | Putative NADH dehydrogenase; (NADH quinone oxidoreductase)(nuoL3-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 5 : Inner membrane protein. | Hypothetical protein; Evidence: Similar to previously reported genes of unknown function. | 0.811 |
BBta_2651 | BBta_2650 | BBta_2651 | BBta_2650 | Putative NADH dehydrogenase; (NADH quinone oxidoreductase)(nuoL3-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 5 : Inner membrane protein. | Hypothetical protein; NUDIX domain; Evidence: Similar to previously reported genes of unknown function; Belongs to the Nudix hydrolase family. | 0.790 |