STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiGThiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (260 aa)    
Predicted Functional Partners:
thiS
Sulfur carrier protein ThiS; Evidence: Function of strongly homologous gene.
 
 
 0.997
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
 0.997
thiO
Glycine oxidase; Evidence: Function of strongly homologous gene; Localization: 2 : Cytoplasmic.
 
 
 0.990
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.987
BBta_0074
Putative Molybdopterin biosynthesis protein moeB; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic.
 
  
 0.956
thiD
Phosphomethylpyrimidine kinase / hydroxymethylpyrimidine kinase; Evidence: Function of homologous gene experimentally demonstrated in an other organism.
 
  
 0.952
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.932
BBta_6930
Putative thiamine phosphate pyrophosphorylase (thiamin phosphate synthase/diphosphorylase); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.856
moaD
Molybdopterin synthase subunit MoaD; Evidence: Function of homologous gene experimentally demonstrated in an other organism.
   
 
 0.852
BBta_2650
Hypothetical protein; NUDIX domain; Evidence: Similar to previously reported genes of unknown function; Belongs to the Nudix hydrolase family.
  
  
 0.839
Your Current Organism:
Bradyrhizobium sp. BTAi1
NCBI taxonomy Id: 288000
Other names: B. sp. BTAi1
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