STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurence
Coexpression
Experiments
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[Homology]
Score
NTE1Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity); Belongs to the NTE family (1441 aa)    
Predicted Functional Partners:
XP_455109.1
KLLA0F00660p; Similar to uniprot|Q02979 Saccharomyces cerevisiae YPL110C Hypothetical ORF
  
 0.987
XP_455985.1
KLLA0F20163p; Similar to uniprot|Q03130 Saccharomyces cerevisiae YOR175C Hypothetical ORF; Belongs to the membrane-bound acyltransferase family
   
 
 0.944
XP_451336.1
Patatin-like phospholipase domain-containing protein; Lipid hydrolase
   
 
 0.930
PLB
Lysophospholipase; Catalyzes the release of fatty acids from lysophospholipids. At acidic pH the enzyme hydrolyzes all phospholipid substrates without metal ion. On the other hand, at alkaline pH the enzyme shows substrate specificity for phosphatidylcholine and lysophosphatidylcholine and requires Ca(2+), Fe(3+), or Al(3+) for the activity
     
 0.905
XP_456211.1
KLLA0F25388p; Some similarities with uniprot|P21957 Saccharomyces cerevisiae YHL020C OPI1 Transcriptional regulator of a variety of genes phosphorylation by protein kinase A stimulates Opi1p function in negative regulation of phospholipid biosynthetic genes
      
 0.819
ISN1
IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation; Belongs to the ISN1 family
 
 
    0.684
XP_454657.1
KLLA0E15687p; Similar to uniprot|P17442 Saccharomyces cerevisiae YGR233C PHO81 Cyclin-dependent kinase (CDK) inhibitor regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels required for derepression of PHO5 transcriptionally regulated by Pho4p and Pho2p
  
 
 0.671
XP_453945.1
KLLA0D19877p; Similar to uniprot|P35688 Saccharomyces cerevisiae YDL240W LRG1 Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity appears to specifically regulate 1 3-beta-glucan synthesis
   
    0.633
XP_456035.1
Phospholipase; Similar to uniprot|P36126 Saccharomyces cerevisiae YKR031C SPO14 Phospholipase D catalyzes the hydrolysis of phosphatidylcholine producing choline and phosphatidic acid involved in Sec14p-independent secretion required for meiosis and spore formation differently regulated in secretion and meiosis
      
 0.613
XP_455516.1
KLLA0F09603p; Highly similar to uniprot|P32473 Saccharomyces cerevisiae YBR221C PDB1 E1 beta subunit of the pyruvate dehydrogenase (PDH) complex which is an evolutionarily- conserved multi-protein complex found in mitochondria
   
   0.606
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 28985
Other names: Candida sphaerica, K. lactis, Kluyveromyces drosophilarum, Kluyveromyces lactis, Kluyveromyces lactis var. drosophilarum, Kluyveromyces lactis var. lactis, Kluyveromyces marxianus lactis, Kluyveromyces marxianus var. drosophilarum, Kluyveromyces marxianus var. lactis
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