STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEM15-aminolevulinate synthase, mitochondrial; Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (570 aa)    
Predicted Functional Partners:
KLLA0_F09273g
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
    
 0.976
KLLA0_D12738g
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.928
KLLA0_F08921g
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.918
SHM1
Serine hydroxymethyltransferase, mitochondrial; Interconversion of serine and glycine.
  
 
 0.918
KLLA0_F08954g
KLLA0F08954p.
    
 0.916
KLLA0_F16775g
KLLA0F16775p.
     
 0.912
KLLA0_E23959g
KLLA0E23959p.
     
 0.912
KLLA0_F02860g
KLLA0F02860p.
  
 
 0.907
KLLA0_D07568g
KLLA0D07568p.
  
 
 0.907
KLLA0_A08492g
KLLA0A08492p.
  
 
 0.907
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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