STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RBD2Rhomboid protein 2; Probable serine protease; Belongs to the peptidase S54 family. (271 aa)    
Predicted Functional Partners:
NOP7
Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
      
 0.760
KLLA0_B04642g
3-hydroxy-3-methylglutaryl coenzyme A reductase.
   
  
 0.727
KLLA0_F05676g
KLLA0F05676p; Belongs to the AAA ATPase family.
    
 
 0.721
KLLA0_D15224g
KLLA0D15224p.
      
 0.583
KLLA0_B03234g
KLLA0B03234p.
    
 
 0.561
ATP3
ATP synthase subunit gamma, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the [...]
   
  
 0.470
KLLA0_D05313g
KLLA0D05313p.
   
 
 0.433
KLLA0_F07139g
KLLA0F07139p.
    
 
 0.427
KLLA0_E04863g
KLLA0E04863p.
      
 0.424
KLLA0_C04532g
KLLA0C04532p.
      
 0.422
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.