STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERG273-keto-steroid reductase; Responsible for the reduction of the keto group on the C-3 of sterols. (346 aa)    
Predicted Functional Partners:
ERG6
Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.
   
 0.999
KLLA0_C18513g
KLLA0C18513p.
   
 0.998
KLLA0_B08085g
KLLA0B08085p; Belongs to the sterol desaturase family.
   
 0.998
KLLA0_F08855g
KLLA0F08855p; Belongs to the sterol desaturase family.
   
 0.990
KLLA0_E03653g
KLLA0E03653p; Belongs to the cytochrome P450 family.
   
 
 0.989
KLLA0_B10175g
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 
 0.989
KLLA0_C12265g
KLLA0C12265p.
   
 
 0.986
KLLA0_E04203g
KLLA0E04203p.
   
 
 0.983
KLLA0_D08866g
KLLA0D08866p.
   
 
 0.983
KLLA0_A05071g
KLLA0A05071p.
   
 
 0.983
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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