STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYM1Protein SYM1; May be involved in cellular response to stress. Required to maintain mitochondrial DNA (mtDNA) integrity and stability (By similarity); Belongs to the peroxisomal membrane protein PXMP2/4 family. (195 aa)    
Predicted Functional Partners:
PEX5
Peroxisomal targeting signal receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
     
 0.622
KLLA0_E16677g
KLLA0E16677p.
     
 0.612
KLLA0_E19735g
KLLA0E19735p.
   
 
 0.611
KLLA0_E07591g
KLLA0E07591p.
     
 0.601
KLLA0_E05017g
KLLA0E05017p.
    
 0.598
ubi4
Polyubiquitin; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys [...]
   
 
  0.597
PEX3
Peroxisomal biogenesis factor 3; Involved in peroxisome biosynthesis; Belongs to the peroxin-3 family.
   
 
 0.556
KLLA0_E12563g
KLLA0E12563p; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.473
KLLA0_E04027g
KLLA0E04027p.
   
 
 0.473
KLLA0_B12540g
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.453
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.