STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Clim_0016PFAM: protein of unknown function UPF0102; KEGG: cph:Cpha266_0037 hypothetical protein; Belongs to the UPF0102 family. (129 aa)    
Predicted Functional Partners:
Clim_0605
KEGG: cph:Cpha266_0558 Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase.
 
  
 0.793
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.785
Clim_2183
PFAM: phosphoribosyltransferase; KEGG: cph:Cpha266_2371 phosphoribosyltransferase.
 
    0.779
Clim_0314
TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: cph:Cpha266_0383 DNA protecting protein DprA.
 
    0.724
Clim_1551
PFAM: ComEC/Rec2-related protein; KEGG: cph:Cpha266_1722 ComEC/Rec2-related protein.
  
    0.634
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.580
Clim_0018
TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: cph:Cpha266_0040 ribonuclease, Rne/Rng family.
 
     0.535
Clim_0019
KEGG: cph:Cpha266_0041 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.
       0.436
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
 
     0.421
Clim_1832
KEGG: cph:Cpha266_1833 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; Stage II sporulation E family protein; PAS fold domain protein; SMART: PAS domain containing protein; protein phosphatase 2C domain protein.
  
    0.405
Your Current Organism:
Chlorobium limicola
NCBI taxonomy Id: 290315
Other names: C. limicola DSM 245, Chlorobium limicola 6330, Chlorobium limicola DSM 245, Chlorobium limicola DSMZ 245(T), Chlorobium limicola str. DSM 245, Chlorobium limicola strain DSM 245
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