node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Clim_0467 | Clim_1248 | Clim_0467 | Clim_1248 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: cph:Cpha266_0530 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.959 |
Clim_0467 | Clim_1967 | Clim_0467 | Clim_1967 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: cph:Cpha266_0530 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: cph:Cpha266_0599 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.923 |
Clim_0467 | argB | Clim_0467 | Clim_1247 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: cph:Cpha266_0530 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.610 |
Clim_0467 | argC | Clim_0467 | Clim_1245 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: cph:Cpha266_0530 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.571 |
Clim_0467 | argD | Clim_0467 | Clim_1957 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: cph:Cpha266_0530 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: cph:Cpha266_0609 acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.428 |
Clim_0467 | argG | Clim_0467 | Clim_1250 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: cph:Cpha266_0530 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | PFAM: argininosuccinate synthase; KEGG: cph:Cpha266_1325 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.985 |
Clim_0467 | argH | Clim_0467 | Clim_1251 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: cph:Cpha266_0530 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: cph:Cpha266_1327 argininosuccinate lyase. | 0.608 |
Clim_0467 | argJ | Clim_0467 | Clim_1246 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: cph:Cpha266_0530 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.448 |
Clim_0467 | purA | Clim_0467 | Clim_2196 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: cph:Cpha266_0530 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.440 |
Clim_1248 | Clim_0467 | Clim_1248 | Clim_0467 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: cph:Cpha266_0530 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.959 |
Clim_1248 | Clim_1967 | Clim_1248 | Clim_1967 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: cph:Cpha266_0599 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.956 |
Clim_1248 | argB | Clim_1248 | Clim_1247 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.992 |
Clim_1248 | argC | Clim_1248 | Clim_1245 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.978 |
Clim_1248 | argD | Clim_1248 | Clim_1957 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: cph:Cpha266_0609 acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.941 |
Clim_1248 | argG | Clim_1248 | Clim_1250 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | PFAM: argininosuccinate synthase; KEGG: cph:Cpha266_1325 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.998 |
Clim_1248 | argH | Clim_1248 | Clim_1251 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: cph:Cpha266_1327 argininosuccinate lyase. | 0.981 |
Clim_1248 | argJ | Clim_1248 | Clim_1246 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.997 |
Clim_1248 | argR | Clim_1248 | Clim_1249 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Arginine repressor, ArgR; Regulates arginine biosynthesis genes. | 0.956 |
Clim_1967 | Clim_0467 | Clim_1967 | Clim_0467 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: cph:Cpha266_0599 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: cph:Cpha266_0530 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.923 |
Clim_1967 | Clim_1248 | Clim_1967 | Clim_1248 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: cph:Cpha266_0599 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.956 |