STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
hprKHpr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (322 aa)    
Predicted Functional Partners:
ABL66431.1
TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: plt:Plut_0167 HPrNtr.
 
 
 
 0.855
ABL64400.1
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
   
 0.791
ABL64624.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cte:CT1631 peptide ABC transporter, permease protein.
       0.762
ABL64623.1
PFAM: extracellular solute-binding protein, family 5; KEGG: plt:Plut_1621 peptide ABC transporter, periplasmic peptide-binding protein.
       0.756
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
       0.660
ABL64626.1
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_3; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: plt:Plut_1618 TPR repeat.
       0.655
ABL64621.1
KEGG: plt:Plut_1623 hypothetical protein.
     
 0.610
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
  
  
 0.610
ABL64422.1
TIGRFAM: PTS system, fructose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: cch:Cag_1468 putative PTS IIA-like nitrogen-regulatory protein PtsN; TC 4.A.2.
 
  
 0.600
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
  
 0.578
Your Current Organism:
Chlorobium phaeobacteroides DSM 266
NCBI taxonomy Id: 290317
Other names: C. phaeobacteroides DSM 266, Chlorobium phaeobacteroides DSMZ 266(T), Chlorobium phaeobacteroides str. DSM 266, Chlorobium phaeobacteroides strain DSM 266
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.