STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucCSuccinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit (392 aa)    
Predicted Functional Partners:
ABL65337.1
PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: plt:Plut_1062 citrate lyase, subunit 2
 0.999
sucD
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
 0.998
ABL64308.1
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cte:CT0163 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit
  
 
 0.970
ABL64627.1
annotation not available
  
 
 0.953
ABL64170.1
Succinate dehydrogenase subunit B; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: plt:Plut_2080 succinate dehydrogenase
  
 0.941
ABL65201.1
KEGG: plt:Plut_1292 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein
  
 0.936
ABL65202.1
Heterodimeric methylmalonyl-CoA mutase small subunit; PFAM: methylmalonyl-CoA mutase; KEGG: plt:Plut_1291 methylmalonyl-CoA mutase
  
 0.920
ABL64307.1
2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: cch:Cag_0365 ferrodoxin oxidoreductase beta subunit
  
 
 0.910
ABL64265.1
3-vinyl bacteriochlorophyllide hydratase; PFAM: 2-vinyl bacteriochlorophyllide hydratase; KEGG: plt:Plut_0408 2-vinyl bacteriochlorophyllide hydratase
     
  0.900
ABL64244.1
KEGG: plt:Plut_1995 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase
 
 0.860
Your Current Organism:
Chlorobium phaeobacteroides DSM266
NCBI taxonomy Id: 290317
Other names: C. phaeobacteroides DSM 266, Chlorobium phaeobacteroides DSM 266, Chlorobium phaeobacteroides DSMZ 266(T), Chlorobium phaeobacteroides str. DSM 266, Chlorobium phaeobacteroides strain DSM 266
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