node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABL64150.1 | ABL64153.1 | Cpha266_0080 | Cpha266_0083 | DNA-cytosine methyltransferase; KEGG: ecp:ECP_4572 modification methylase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | KEGG: lpf:lpl0145 DNA (cytosine-5-)-methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase. | 0.956 |
ABL64150.1 | ABL64799.1 | Cpha266_0080 | Cpha266_0746 | DNA-cytosine methyltransferase; KEGG: ecp:ECP_4572 modification methylase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | 0.900 |
ABL64150.1 | ahcY | Cpha266_0080 | Cpha266_0921 | DNA-cytosine methyltransferase; KEGG: ecp:ECP_4572 modification methylase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.903 |
ABL64150.1 | metK | Cpha266_0080 | Cpha266_0922 | DNA-cytosine methyltransferase; KEGG: ecp:ECP_4572 modification methylase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.914 |
ABL64153.1 | ABL64150.1 | Cpha266_0083 | Cpha266_0080 | KEGG: lpf:lpl0145 DNA (cytosine-5-)-methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase. | DNA-cytosine methyltransferase; KEGG: ecp:ECP_4572 modification methylase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.956 |
ABL64153.1 | ABL64799.1 | Cpha266_0083 | Cpha266_0746 | KEGG: lpf:lpl0145 DNA (cytosine-5-)-methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase. | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | 0.900 |
ABL64153.1 | ahcY | Cpha266_0083 | Cpha266_0921 | KEGG: lpf:lpl0145 DNA (cytosine-5-)-methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.903 |
ABL64153.1 | metK | Cpha266_0083 | Cpha266_0922 | KEGG: lpf:lpl0145 DNA (cytosine-5-)-methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.914 |
ABL64799.1 | ABL64150.1 | Cpha266_0746 | Cpha266_0080 | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | DNA-cytosine methyltransferase; KEGG: ecp:ECP_4572 modification methylase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.900 |
ABL64799.1 | ABL64153.1 | Cpha266_0746 | Cpha266_0083 | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | KEGG: lpf:lpl0145 DNA (cytosine-5-)-methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase. | 0.900 |
ABL64799.1 | ABL66114.1 | Cpha266_0746 | Cpha266_2102 | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.900 |
ABL64799.1 | metK | Cpha266_0746 | Cpha266_0922 | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.900 |
ABL65740.1 | ABL66114.1 | Cpha266_1723 | Cpha266_2102 | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: cch:Cag_1108 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.997 |
ABL65740.1 | ahcY | Cpha266_1723 | Cpha266_0921 | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: cch:Cag_1108 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.452 |
ABL65740.1 | glyA | Cpha266_1723 | Cpha266_0601 | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: cch:Cag_1108 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.950 |
ABL65740.1 | metK | Cpha266_1723 | Cpha266_0922 | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: cch:Cag_1108 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.749 |
ABL66114.1 | ABL64799.1 | Cpha266_2102 | Cpha266_0746 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | 0.900 |
ABL66114.1 | ABL65740.1 | Cpha266_2102 | Cpha266_1723 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: cch:Cag_1108 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.997 |
ABL66114.1 | ahcY | Cpha266_2102 | Cpha266_0921 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.948 |
ABL66114.1 | glyA | Cpha266_2102 | Cpha266_0601 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.936 |