node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABL64406.1 | ABL64460.1 | Cpha266_0347 | Cpha266_0401 | PFAM: lipid A biosynthesis acyltransferase; KEGG: cch:Cag_1483 acyltransferase, HtrB/MsbB family. | KpsF/GutQ family protein; KEGG: cch:Cag_0467 KpsF/GutQ; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | 0.726 |
ABL64406.1 | ABL64469.1 | Cpha266_0347 | Cpha266_0411 | PFAM: lipid A biosynthesis acyltransferase; KEGG: cch:Cag_1483 acyltransferase, HtrB/MsbB family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.825 |
ABL64406.1 | ABL65795.1 | Cpha266_0347 | Cpha266_1778 | PFAM: lipid A biosynthesis acyltransferase; KEGG: cch:Cag_1483 acyltransferase, HtrB/MsbB family. | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.978 |
ABL64406.1 | kdsB | Cpha266_0347 | Cpha266_2079 | PFAM: lipid A biosynthesis acyltransferase; KEGG: cch:Cag_1483 acyltransferase, HtrB/MsbB family. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.606 |
ABL64406.1 | lpxA | Cpha266_0347 | Cpha266_2373 | PFAM: lipid A biosynthesis acyltransferase; KEGG: cch:Cag_1483 acyltransferase, HtrB/MsbB family. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.797 |
ABL64406.1 | lpxC | Cpha266_0347 | Cpha266_0541 | PFAM: lipid A biosynthesis acyltransferase; KEGG: cch:Cag_1483 acyltransferase, HtrB/MsbB family. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. | 0.648 |
ABL64406.1 | lpxK | Cpha266_0347 | Cpha266_0526 | PFAM: lipid A biosynthesis acyltransferase; KEGG: cch:Cag_1483 acyltransferase, HtrB/MsbB family. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.804 |
ABL64437.1 | lpxA | Cpha266_0378 | Cpha266_2373 | UDP-N-acetylglucosamine pyrophosphorylase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Nucleotidyl transferase; KEGG: cte:CT0251 UDP-N-acetylglucosamine pyrophosphorylase. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.830 |
ABL64437.1 | murA | Cpha266_0378 | Cpha266_0807 | UDP-N-acetylglucosamine pyrophosphorylase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Nucleotidyl transferase; KEGG: cte:CT0251 UDP-N-acetylglucosamine pyrophosphorylase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.934 |
ABL64460.1 | ABL64406.1 | Cpha266_0401 | Cpha266_0347 | KpsF/GutQ family protein; KEGG: cch:Cag_0467 KpsF/GutQ; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | PFAM: lipid A biosynthesis acyltransferase; KEGG: cch:Cag_1483 acyltransferase, HtrB/MsbB family. | 0.726 |
ABL64460.1 | ABL64469.1 | Cpha266_0401 | Cpha266_0411 | KpsF/GutQ family protein; KEGG: cch:Cag_0467 KpsF/GutQ; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.854 |
ABL64460.1 | ABL65795.1 | Cpha266_0401 | Cpha266_1778 | KpsF/GutQ family protein; KEGG: cch:Cag_0467 KpsF/GutQ; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.869 |
ABL64460.1 | ABL66264.1 | Cpha266_0401 | Cpha266_2272 | KpsF/GutQ family protein; KEGG: cch:Cag_0467 KpsF/GutQ; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cte:CT1901 ABC transporter, ATP-binding protein. | 0.609 |
ABL64460.1 | kdsB | Cpha266_0401 | Cpha266_2079 | KpsF/GutQ family protein; KEGG: cch:Cag_0467 KpsF/GutQ; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.875 |
ABL64460.1 | lpxA | Cpha266_0401 | Cpha266_2373 | KpsF/GutQ family protein; KEGG: cch:Cag_0467 KpsF/GutQ; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.845 |
ABL64460.1 | lpxC | Cpha266_0401 | Cpha266_0541 | KpsF/GutQ family protein; KEGG: cch:Cag_0467 KpsF/GutQ; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. | 0.668 |
ABL64460.1 | lpxK | Cpha266_0401 | Cpha266_0526 | KpsF/GutQ family protein; KEGG: cch:Cag_0467 KpsF/GutQ; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.871 |
ABL64469.1 | ABL64406.1 | Cpha266_0411 | Cpha266_0347 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | PFAM: lipid A biosynthesis acyltransferase; KEGG: cch:Cag_1483 acyltransferase, HtrB/MsbB family. | 0.825 |
ABL64469.1 | ABL64460.1 | Cpha266_0411 | Cpha266_0401 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | KpsF/GutQ family protein; KEGG: cch:Cag_0467 KpsF/GutQ; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | 0.854 |
ABL64469.1 | ABL65795.1 | Cpha266_0411 | Cpha266_1778 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.849 |