node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABL65337.1 | nadK | Cpha266_1306 | Cpha266_2573 | PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: plt:Plut_1062 citrate lyase, subunit 2. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.405 |
ABL65337.1 | ribBA | Cpha266_1306 | Cpha266_0600 | PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: plt:Plut_1062 citrate lyase, subunit 2. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.422 |
ABL66558.1 | ABL66560.1 | Cpha266_2570 | Cpha266_2572 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | PFAM: Prephenate dehydrogenase; KEGG: cch:Cag_0018 prephenate dehydrogenase. | 0.556 |
ABL66558.1 | ABL66562.1 | Cpha266_2570 | Cpha266_2574 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | KEGG: cch:Cag_0020 hypothetical protein. | 0.429 |
ABL66558.1 | nadK | Cpha266_2570 | Cpha266_2573 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.561 |
ABL66558.1 | pyrE | Cpha266_2570 | Cpha266_2571 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.560 |
ABL66560.1 | ABL66558.1 | Cpha266_2572 | Cpha266_2570 | PFAM: Prephenate dehydrogenase; KEGG: cch:Cag_0018 prephenate dehydrogenase. | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.556 |
ABL66560.1 | ABL66562.1 | Cpha266_2572 | Cpha266_2574 | PFAM: Prephenate dehydrogenase; KEGG: cch:Cag_0018 prephenate dehydrogenase. | KEGG: cch:Cag_0020 hypothetical protein. | 0.668 |
ABL66560.1 | nadK | Cpha266_2572 | Cpha266_2573 | PFAM: Prephenate dehydrogenase; KEGG: cch:Cag_0018 prephenate dehydrogenase. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.798 |
ABL66560.1 | pyrE | Cpha266_2572 | Cpha266_2571 | PFAM: Prephenate dehydrogenase; KEGG: cch:Cag_0018 prephenate dehydrogenase. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.795 |
ABL66562.1 | ABL66558.1 | Cpha266_2574 | Cpha266_2570 | KEGG: cch:Cag_0020 hypothetical protein. | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.429 |
ABL66562.1 | ABL66560.1 | Cpha266_2574 | Cpha266_2572 | KEGG: cch:Cag_0020 hypothetical protein. | PFAM: Prephenate dehydrogenase; KEGG: cch:Cag_0018 prephenate dehydrogenase. | 0.668 |
ABL66562.1 | nadK | Cpha266_2574 | Cpha266_2573 | KEGG: cch:Cag_0020 hypothetical protein. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.655 |
ABL66562.1 | pyrE | Cpha266_2574 | Cpha266_2571 | KEGG: cch:Cag_0020 hypothetical protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.719 |
dxs | nadK | Cpha266_0671 | Cpha266_2573 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.635 |
dxs | ribBA | Cpha266_0671 | Cpha266_0600 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.479 |
ffh | nadK | Cpha266_1525 | Cpha266_2573 | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.497 |
nadD | nadE | Cpha266_2703 | Cpha266_0810 | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.947 |
nadD | nadK | Cpha266_2703 | Cpha266_2573 | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.936 |
nadD | ribBA | Cpha266_2703 | Cpha266_0600 | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.462 |