STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lipALipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (284 aa)    
Predicted Functional Partners:
Cvib_0724
PFAM: biotin/lipoate A/B protein ligase; KEGG: plt:Plut_1329 lipoate-protein ligase A-like.
 
 
 0.942
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.889
Cvib_1060
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: plt:Plut_0784 dihydrolipoamide dehydrogenase.
 
  
 0.653
Cvib_0855
PFAM: NAD-dependent epimerase/dehydratase; NmrA family protein; KEGG: plt:Plut_1086 hypothetical protein.
       0.643
Cvib_0856
KEGG: plt:Plut_1085 hypothetical protein.
       0.643
Cvib_0859
KEGG: plt:Plut_1082 putative ABC transport system, lipoprotein.
     
 0.545
Cvib_0858
PFAM: regulatory protein, TetR; KEGG: plt:Plut_1083 putative transcriptional regulator, TetR family.
       0.527
Cvib_0860
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: plt:Plut_1081 ATPase.
       0.527
Cvib_0861
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: plt:Plut_1080 ATPase.
       0.527
Cvib_0862
PFAM: ABC-2 type transporter; KEGG: plt:Plut_1079 putative ABC transporter ATP-binding protein or permease protein.
       0.527
Your Current Organism:
Chlorobium phaeovibrioides
NCBI taxonomy Id: 290318
Other names: C. phaeovibrioides DSM 265, Chlorobium phaeovibrioides DSM 265, Chlorobium vibrioforme f. thiosulfatophilum DSM 265, Prosthecochloris vibrioformis DSM 265
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.