STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (309 aa)    
Predicted Functional Partners:
Cvib_0866
PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: plt:Plut_1062 citrate lyase, subunit 2.
  
 0.999
Cvib_1020
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.997
Cvib_0401
KEGG: plt:Plut_0336 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.972
Cvib_0867
ATP citrate lyase subunit 1; PFAM: ATP-grasp domain protein; KEGG: plt:Plut_1061 citrate lyase, subunit 1.
  
 0.946
Cvib_1018
PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; KEGG: plt:Plut_1267 oxaloacetate decarboxylase, alpha subunit.
    
 0.943
Cvib_0768
PFAM: aminotransferase, class I and II; KEGG: plt:Plut_1189 aspartate aminotransferase, putative.
  
 0.921
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.919
Cvib_0558
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: plt:Plut_0502 glutamate synthase (ferredoxin).
  
 
 0.902
Cvib_1017
KEGG: plt:Plut_1266 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit.
     
 0.901
Cvib_1251
KEGG: plt:Plut_1434 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit.
     
 0.901
Your Current Organism:
Chlorobium phaeovibrioides
NCBI taxonomy Id: 290318
Other names: C. phaeovibrioides DSM 265, Chlorobium phaeovibrioides DSM 265, Chlorobium vibrioforme f. thiosulfatophilum DSM 265, Prosthecochloris vibrioformis DSM 265
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