STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mltFHypothetical protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. (515 aa)    
Predicted Functional Partners:
purL
Hypothetical protein; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
     
 0.754
CKO_00144
Hypothetical protein; COG: COG3071 Uncharacterized enzyme of heme biosynthesis.
  
   
 0.547
lolB
Hypothetical protein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
 
     0.537
CKO_02972
Hypothetical protein; KEGG: sty:STY0281 3.2e-229 mltD; membrane-bound lytic murein transglycosylase d precursor K08307; COG: COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).
 
   
 0.529
nudJ
Hypothetical protein; KEGG: stm:STM1235 1.5e-73 ymfB; putative MutT-like protein; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: Cytoplasmic, score:8.96; Belongs to the Nudix hydrolase family. NudJ subfamily.
  
 
   0.507
CKO_00211
Hypothetical protein; COG: COG3026 Negative regulator of sigma E activity; Psort location: Periplasmic, score:9.76.
  
     0.490
CKO_00145
Hypothetical protein; KEGG: stm:STM3936 4.6e-182 hemX; uroporphyrinogen III methylase K02496; COG: COG2959 Uncharacterized enzyme of heme biosynthesis.
  
     0.468
CKO_02970
Hypothetical protein; KEGG: vfi:VF1937 7.6e-47 methyltransferase K00599; COG: COG0500 SAM-dependent methyltransferases.
  
    0.434
ftsL
Hypothetical protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
     0.407
mltC
Hypothetical protein; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
 
   
 0.400
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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