STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_00504Hypothetical protein; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates. (199 aa)    
Predicted Functional Partners:
surE
Hypothetical protein; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
     
 0.925
CKO_03418
Hypothetical protein; KEGG: spt:SPA4373 3.0e-107 yjjG; hypothetical protein K08723; COG: COG1011 Predicted hydrolase (HAD superfamily).
     
 0.921
CKO_02669
Hypothetical protein; KEGG: sec:SC0536 3.0e-281 ushA; UDP-sugar hydrolase 5'-nucleotidase K01081:K08077; COG: COG0737 5-nucleotidase/2,3-cyclic phosphodiesterase and related esterases; Psort location: Periplasmic, score:10.00; Belongs to the 5'-nucleotidase family.
     
 0.920
CKO_04822
Hypothetical protein; KEGG: rso:RSc2880 1.3e-07 gph, RS00222; probable phosphoglycolate phosphatase protein K01091; COG: COG1011 Predicted hydrolase (HAD superfamily); Psort location: Cytoplasmic, score:8.96.
     
 0.920
deoD
Hypothetical protein; KEGG: sty:STY4921 3.0e-123 deoD, pup; purine nucleoside phosphorylase K03784; COG: COG0813 Purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score:8.96.
     
 0.906
tmk
Hypothetical protein; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
  0.904
tdk
Hypothetical protein; KEGG: sfx:S1324 2.0e-101 tdk; thymidine kinase K00857; COG: COG1435 Thymidine kinase.
    
  0.902
cdd
Hypothetical protein; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
     
 0.901
cmk
Hypothetical protein; KEGG: eco:b0910 1.4e-111 cmk, mssA, ycaF, ycaG; cytidine monophosphate (CMP) kinase K00945; COG: COG0283 Cytidylate kinase.
     
 0.901
dut
Hypothetical protein; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
    
  0.901
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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