node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAur_0850 | AAur_2175 | AAur_0850 | AAur_2175 | Conserved hypothetical protein. | Putative proteasome component; Identified by match to protein family HMM PF03136; match to protein family HMM PF03316. | 0.698 |
AAur_0850 | arc | AAur_0850 | AAur_2174 | Conserved hypothetical protein. | Putative ATPase, AAA family domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.791 |
AAur_0850 | pafA | AAur_0850 | AAur_2179 | Conserved hypothetical protein. | Putative proteasome component; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.747 |
AAur_0850 | prcA | AAur_0850 | AAur_2178 | Conserved hypothetical protein. | Putative 20S proteasome alpha-subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.989 |
AAur_0850 | prcB | AAur_0850 | AAur_2177 | Conserved hypothetical protein. | Putative 20S proteasome beta-subunit precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.928 |
AAur_2173 | AAur_2175 | AAur_2173 | AAur_2175 | Conserved hypothetical protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | Putative proteasome component; Identified by match to protein family HMM PF03136; match to protein family HMM PF03316. | 0.786 |
AAur_2173 | arc | AAur_2173 | AAur_2174 | Conserved hypothetical protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | Putative ATPase, AAA family domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.806 |
AAur_2173 | pafA | AAur_2173 | AAur_2179 | Conserved hypothetical protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | Putative proteasome component; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.704 |
AAur_2173 | prcA | AAur_2173 | AAur_2178 | Conserved hypothetical protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | Putative 20S proteasome alpha-subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.562 |
AAur_2173 | prcB | AAur_2173 | AAur_2177 | Conserved hypothetical protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | Putative 20S proteasome beta-subunit precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.622 |
AAur_2175 | AAur_0850 | AAur_2175 | AAur_0850 | Putative proteasome component; Identified by match to protein family HMM PF03136; match to protein family HMM PF03316. | Conserved hypothetical protein. | 0.698 |
AAur_2175 | AAur_2173 | AAur_2175 | AAur_2173 | Putative proteasome component; Identified by match to protein family HMM PF03136; match to protein family HMM PF03316. | Conserved hypothetical protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.786 |
AAur_2175 | arc | AAur_2175 | AAur_2174 | Putative proteasome component; Identified by match to protein family HMM PF03136; match to protein family HMM PF03316. | Putative ATPase, AAA family domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.976 |
AAur_2175 | pafA | AAur_2175 | AAur_2179 | Putative proteasome component; Identified by match to protein family HMM PF03136; match to protein family HMM PF03316. | Putative proteasome component; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.746 |
AAur_2175 | prcA | AAur_2175 | AAur_2178 | Putative proteasome component; Identified by match to protein family HMM PF03136; match to protein family HMM PF03316. | Putative 20S proteasome alpha-subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.950 |
AAur_2175 | prcB | AAur_2175 | AAur_2177 | Putative proteasome component; Identified by match to protein family HMM PF03136; match to protein family HMM PF03316. | Putative 20S proteasome beta-subunit precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.945 |
AAur_2651 | AAur_3806 | AAur_2651 | AAur_3806 | Trypsin-like serine protease; Identified by match to protein family HMM PF00089; match to protein family HMM PF00595. | Putative ATPase domain, AAA family protein; Identified by match to protein family HMM PF00004; match to protein family HMM PF00583; Belongs to the AAA ATPase family. | 0.407 |
AAur_2651 | arc | AAur_2651 | AAur_2174 | Trypsin-like serine protease; Identified by match to protein family HMM PF00089; match to protein family HMM PF00595. | Putative ATPase, AAA family domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.738 |
AAur_2651 | glpK | AAur_2651 | AAur_2247 | Trypsin-like serine protease; Identified by match to protein family HMM PF00089; match to protein family HMM PF00595. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.635 |
AAur_2651 | prcA | AAur_2651 | AAur_2178 | Trypsin-like serine protease; Identified by match to protein family HMM PF00089; match to protein family HMM PF00595. | Putative 20S proteasome alpha-subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.458 |