STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAur_3341Putative ATP-dependent RNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. (780 aa)    
Predicted Functional Partners:
AAur_3340
Identified by match to protein family HMM PF00583.
       0.590
AAur_2451
Conserved hypothetical protein; Belongs to the UPF0109 family.
  
   
 0.548
AAur_4206
Putative jag-like protein; Identified by match to protein family HMM PF01424.
  
   
 0.511
AAur_3339
Putative rhodanese-like domain protein; Identified by match to protein family HMM PF00581; Belongs to the UPF0176 family.
       0.452
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.426
Your Current Organism:
Paenarthrobacter aurescens
NCBI taxonomy Id: 290340
Other names: Arthrobacter aurescens TC1, P. aurescens TC1, Paenarthrobacter aurescens TC1
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