node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adeh_0942 | gcvPA | Adeh_0942 | Adeh_1243 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.928 |
Adeh_0942 | gcvPB | Adeh_0942 | Adeh_1242 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.931 |
Adeh_0942 | glyA | Adeh_0942 | Adeh_2744 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.932 |
Adeh_1822 | Adeh_2003 | Adeh_1822 | Adeh_2003 | Dihydrolipoamide dehydrogenase. | Glycine cleavage H-protein. | 0.935 |
Adeh_1822 | Adeh_2005 | Adeh_1822 | Adeh_2005 | Dihydrolipoamide dehydrogenase. | Glycine cleavage H-protein. | 0.935 |
Adeh_1822 | Adeh_2307 | Adeh_1822 | Adeh_2307 | Dihydrolipoamide dehydrogenase. | Glycine cleavage H-protein. | 0.935 |
Adeh_1822 | Adeh_4119 | Adeh_1822 | Adeh_4119 | Dihydrolipoamide dehydrogenase. | Glycine cleavage H-protein. | 0.935 |
Adeh_1822 | gcvH | Adeh_1822 | Adeh_1244 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.970 |
Adeh_1822 | gcvPA | Adeh_1822 | Adeh_1243 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.936 |
Adeh_1822 | gcvPB | Adeh_1822 | Adeh_1242 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.937 |
Adeh_1822 | gcvT | Adeh_1822 | Adeh_1245 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.963 |
Adeh_1822 | glyA | Adeh_1822 | Adeh_2744 | Dihydrolipoamide dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.933 |
Adeh_2003 | Adeh_1822 | Adeh_2003 | Adeh_1822 | Glycine cleavage H-protein. | Dihydrolipoamide dehydrogenase. | 0.935 |
Adeh_2003 | Adeh_2005 | Adeh_2003 | Adeh_2005 | Glycine cleavage H-protein. | Glycine cleavage H-protein. | 0.964 |
Adeh_2003 | Adeh_2307 | Adeh_2003 | Adeh_2307 | Glycine cleavage H-protein. | Glycine cleavage H-protein. | 0.932 |
Adeh_2003 | Adeh_4119 | Adeh_2003 | Adeh_4119 | Glycine cleavage H-protein. | Glycine cleavage H-protein. | 0.915 |
Adeh_2003 | gcvH | Adeh_2003 | Adeh_1244 | Glycine cleavage H-protein. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.921 |
Adeh_2003 | gcvPA | Adeh_2003 | Adeh_1243 | Glycine cleavage H-protein. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.983 |
Adeh_2003 | gcvPB | Adeh_2003 | Adeh_1242 | Glycine cleavage H-protein. | Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.992 |
Adeh_2003 | gcvT | Adeh_2003 | Adeh_1245 | Glycine cleavage H-protein. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.995 |