node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adeh_1291 | Adeh_2496 | Adeh_1291 | Adeh_2496 | Chaperone DnaJ-like protein. | Thioredoxin; Belongs to the thioredoxin family. | 0.535 |
Adeh_1291 | grpE | Adeh_1291 | Adeh_1772 | Chaperone DnaJ-like protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.821 |
Adeh_1291 | hslU | Adeh_1291 | Adeh_2693 | Chaperone DnaJ-like protein. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.556 |
Adeh_1291 | hslV | Adeh_1291 | Adeh_2694 | Chaperone DnaJ-like protein. | ATP dependent peptidase CodWX, CodW component, Threonine peptidase, MEROPS family T01B; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.469 |
Adeh_1564 | Adeh_2496 | Adeh_1564 | Adeh_2496 | Ferric uptake regulator, Fur family; Belongs to the Fur family. | Thioredoxin; Belongs to the thioredoxin family. | 0.576 |
Adeh_2495 | Adeh_2496 | Adeh_2495 | Adeh_2496 | Hypothetical protein. | Thioredoxin; Belongs to the thioredoxin family. | 0.533 |
Adeh_2496 | Adeh_1291 | Adeh_2496 | Adeh_1291 | Thioredoxin; Belongs to the thioredoxin family. | Chaperone DnaJ-like protein. | 0.535 |
Adeh_2496 | Adeh_1564 | Adeh_2496 | Adeh_1564 | Thioredoxin; Belongs to the thioredoxin family. | Ferric uptake regulator, Fur family; Belongs to the Fur family. | 0.576 |
Adeh_2496 | Adeh_2495 | Adeh_2496 | Adeh_2495 | Thioredoxin; Belongs to the thioredoxin family. | Hypothetical protein. | 0.533 |
Adeh_2496 | Adeh_3951 | Adeh_2496 | Adeh_3951 | Thioredoxin; Belongs to the thioredoxin family. | Thioredoxin reductase. | 0.986 |
Adeh_2496 | fur | Adeh_2496 | Adeh_3806 | Thioredoxin; Belongs to the thioredoxin family. | Ferric uptake regulator, Fur family; Belongs to the Fur family. | 0.576 |
Adeh_2496 | grpE | Adeh_2496 | Adeh_1772 | Thioredoxin; Belongs to the thioredoxin family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.521 |
Adeh_2496 | hslU | Adeh_2496 | Adeh_2693 | Thioredoxin; Belongs to the thioredoxin family. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.551 |
Adeh_2496 | hslV | Adeh_2496 | Adeh_2694 | Thioredoxin; Belongs to the thioredoxin family. | ATP dependent peptidase CodWX, CodW component, Threonine peptidase, MEROPS family T01B; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.542 |
Adeh_2496 | rho | Adeh_2496 | Adeh_0690 | Thioredoxin; Belongs to the thioredoxin family. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.647 |
Adeh_2496 | rho-2 | Adeh_2496 | Adeh_1137 | Thioredoxin; Belongs to the thioredoxin family. | H+-transporting two-sector ATPase, alpha/beta subunit; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.547 |
Adeh_3951 | Adeh_2496 | Adeh_3951 | Adeh_2496 | Thioredoxin reductase. | Thioredoxin; Belongs to the thioredoxin family. | 0.986 |
fur | Adeh_2496 | Adeh_3806 | Adeh_2496 | Ferric uptake regulator, Fur family; Belongs to the Fur family. | Thioredoxin; Belongs to the thioredoxin family. | 0.576 |
grpE | Adeh_1291 | Adeh_1772 | Adeh_1291 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Chaperone DnaJ-like protein. | 0.821 |
grpE | Adeh_2496 | Adeh_1772 | Adeh_2496 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Thioredoxin; Belongs to the thioredoxin family. | 0.521 |