node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adeh_0127 | apt | Adeh_0127 | Adeh_0751 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.932 |
Adeh_0127 | gmk | Adeh_0127 | Adeh_2606 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.932 |
Adeh_0127 | gpt | Adeh_0127 | Adeh_1006 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.930 |
Adeh_0127 | guaA | Adeh_0127 | Adeh_2348 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.946 |
Adeh_1613 | Adeh_2550 | Adeh_1613 | Adeh_2550 | Ribonucleoside diphosphate reductase, B12-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.901 |
Adeh_1613 | Adeh_4234 | Adeh_1613 | Adeh_4234 | Ribonucleoside diphosphate reductase, B12-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.909 |
Adeh_1613 | gmk | Adeh_1613 | Adeh_2606 | Ribonucleoside diphosphate reductase, B12-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.915 |
Adeh_1613 | guaA | Adeh_1613 | Adeh_2348 | Ribonucleoside diphosphate reductase, B12-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.563 |
Adeh_1613 | ndk | Adeh_1613 | Adeh_1629 | Ribonucleoside diphosphate reductase, B12-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.918 |
Adeh_2550 | Adeh_1613 | Adeh_2550 | Adeh_1613 | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleoside diphosphate reductase, B12-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.901 |
Adeh_2550 | Adeh_4234 | Adeh_2550 | Adeh_4234 | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.908 |
Adeh_2550 | gmk | Adeh_2550 | Adeh_2606 | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.929 |
Adeh_2550 | ndk | Adeh_2550 | Adeh_1629 | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.918 |
Adeh_2607 | gmk | Adeh_2607 | Adeh_2606 | Conserved hypothetical protein. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.954 |
Adeh_3683 | gmk | Adeh_3683 | Adeh_2606 | Deoxynucleoside kinase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.929 |
Adeh_3683 | guaA | Adeh_3683 | Adeh_2348 | Deoxynucleoside kinase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.415 |
Adeh_4234 | Adeh_1613 | Adeh_4234 | Adeh_1613 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Ribonucleoside diphosphate reductase, B12-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.909 |
Adeh_4234 | Adeh_2550 | Adeh_4234 | Adeh_2550 | Pyruvate kinase; Belongs to the pyruvate kinase family. | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.908 |
Adeh_4234 | gmk | Adeh_4234 | Adeh_2606 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.938 |
Adeh_4234 | guaA | Adeh_4234 | Adeh_2348 | Pyruvate kinase; Belongs to the pyruvate kinase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.614 |