STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slcCD-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein; Dehydrogenase of the (R,S)-sulfolactate degradation pathway that only acts on the (S)-enantiomer of 3-sulfolactate. Together with ComC, provides a racemase system that converts (2S)-3-sulfolactate to (2R)-3-sulfolactate, which is degraded further by (2R)-sulfolactate sulfo-lyase. Specific for NAD. Also able to form sulfolactate from sulfopyruvate. (309 aa)    
Predicted Functional Partners:
comC
Malate dehydrogenase (NADP+); Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate. Together with SlcC, provides a racemase system that converts (2S)-3- sulfolactate to (2R)-3-sulfolactate, which is degraded further by (2R)- sulfolactate sulfo-lyase; Belongs to the LDH2/MDH2 oxidoreductase family.
 
  
 0.995
Csal_1034
Aminotransferase.
 
 0.924
suyB
Altronate dehydratase; Together with SuyA, desulfonates sulfolactate to pyruvate and sulfite; Belongs to the UxaA family.
 
 
 0.859
Csal_1764
Transcriptional regulator, GntR family.
 
   
 0.797
Csal_1769
Hypothetical protein.
 
     0.786
Csal_1768
Protein of unknown function DUF112, transmembrane.
       0.718
Csal_1043
Periplasmic binding protein.
      
 0.700
Csal_1050
Periplasmic binding protein.
      
 0.700
Csal_1492
Periplasmic binding protein.
      
 0.700
serC
Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.673
Your Current Organism:
Chromohalobacter salexigens
NCBI taxonomy Id: 290398
Other names: C. salexigens DSM 3043, Chromohalobacter salexigens 1H11, Chromohalobacter salexigens DSM 3043
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