node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Csal_0168 | Csal_2339 | Csal_0168 | Csal_2339 | TspO and MBR like protein. | Proline racemase; In vitro, catalyzes the epimerization of trans-4-hydroxy-L- proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp), albeit with very low efficiency. The physiological substrate may be different. Displays neither proline racemase activity nor t3LHyp dehydratase activity. | 0.422 |
Csal_0168 | Csal_2705 | Csal_0168 | Csal_2705 | TspO and MBR like protein. | Proline racemase; Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Displays no proline racemase activity. | 0.422 |
Csal_1140 | Csal_2339 | Csal_1140 | Csal_2339 | Aldehyde dehydrogenase. | Proline racemase; In vitro, catalyzes the epimerization of trans-4-hydroxy-L- proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp), albeit with very low efficiency. The physiological substrate may be different. Displays neither proline racemase activity nor t3LHyp dehydratase activity. | 0.529 |
Csal_1140 | Csal_2705 | Csal_1140 | Csal_2705 | Aldehyde dehydrogenase. | Proline racemase; Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Displays no proline racemase activity. | 0.713 |
Csal_1140 | Csal_2706 | Csal_1140 | Csal_2706 | Aldehyde dehydrogenase. | Dihydrodipicolinate synthetase; Belongs to the DapA family. | 0.523 |
Csal_1724 | Csal_2339 | Csal_1724 | Csal_2339 | FAD dependent oxidoreductase. | Proline racemase; In vitro, catalyzes the epimerization of trans-4-hydroxy-L- proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp), albeit with very low efficiency. The physiological substrate may be different. Displays neither proline racemase activity nor t3LHyp dehydratase activity. | 0.484 |
Csal_1724 | Csal_2705 | Csal_1724 | Csal_2705 | FAD dependent oxidoreductase. | Proline racemase; Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Displays no proline racemase activity. | 0.560 |
Csal_1752 | Csal_2339 | Csal_1752 | Csal_2339 | Malate/L-lactate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family. | Proline racemase; In vitro, catalyzes the epimerization of trans-4-hydroxy-L- proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp), albeit with very low efficiency. The physiological substrate may be different. Displays neither proline racemase activity nor t3LHyp dehydratase activity. | 0.725 |
Csal_1752 | Csal_2705 | Csal_1752 | Csal_2705 | Malate/L-lactate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family. | Proline racemase; Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Displays no proline racemase activity. | 0.725 |
Csal_1752 | proS | Csal_1752 | Csal_2139 | Malate/L-lactate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.615 |
Csal_2339 | Csal_0168 | Csal_2339 | Csal_0168 | Proline racemase; In vitro, catalyzes the epimerization of trans-4-hydroxy-L- proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp), albeit with very low efficiency. The physiological substrate may be different. Displays neither proline racemase activity nor t3LHyp dehydratase activity. | TspO and MBR like protein. | 0.422 |
Csal_2339 | Csal_1140 | Csal_2339 | Csal_1140 | Proline racemase; In vitro, catalyzes the epimerization of trans-4-hydroxy-L- proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp), albeit with very low efficiency. The physiological substrate may be different. Displays neither proline racemase activity nor t3LHyp dehydratase activity. | Aldehyde dehydrogenase. | 0.529 |
Csal_2339 | Csal_1724 | Csal_2339 | Csal_1724 | Proline racemase; In vitro, catalyzes the epimerization of trans-4-hydroxy-L- proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp), albeit with very low efficiency. The physiological substrate may be different. Displays neither proline racemase activity nor t3LHyp dehydratase activity. | FAD dependent oxidoreductase. | 0.484 |
Csal_2339 | Csal_1752 | Csal_2339 | Csal_1752 | Proline racemase; In vitro, catalyzes the epimerization of trans-4-hydroxy-L- proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp), albeit with very low efficiency. The physiological substrate may be different. Displays neither proline racemase activity nor t3LHyp dehydratase activity. | Malate/L-lactate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family. | 0.725 |
Csal_2339 | Csal_2340 | Csal_2339 | Csal_2340 | Proline racemase; In vitro, catalyzes the epimerization of trans-4-hydroxy-L- proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp), albeit with very low efficiency. The physiological substrate may be different. Displays neither proline racemase activity nor t3LHyp dehydratase activity. | Alcohol dehydrogenase, zinc-binding protein. | 0.936 |
Csal_2339 | Csal_2705 | Csal_2339 | Csal_2705 | Proline racemase; In vitro, catalyzes the epimerization of trans-4-hydroxy-L- proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp), albeit with very low efficiency. The physiological substrate may be different. Displays neither proline racemase activity nor t3LHyp dehydratase activity. | Proline racemase; Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Displays no proline racemase activity. | 0.489 |
Csal_2339 | Csal_2706 | Csal_2339 | Csal_2706 | Proline racemase; In vitro, catalyzes the epimerization of trans-4-hydroxy-L- proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp), albeit with very low efficiency. The physiological substrate may be different. Displays neither proline racemase activity nor t3LHyp dehydratase activity. | Dihydrodipicolinate synthetase; Belongs to the DapA family. | 0.487 |
Csal_2339 | Csal_2708 | Csal_2339 | Csal_2708 | Proline racemase; In vitro, catalyzes the epimerization of trans-4-hydroxy-L- proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp), albeit with very low efficiency. The physiological substrate may be different. Displays neither proline racemase activity nor t3LHyp dehydratase activity. | D-amino-acid dehydrogenase. | 0.492 |
Csal_2339 | proS | Csal_2339 | Csal_2139 | Proline racemase; In vitro, catalyzes the epimerization of trans-4-hydroxy-L- proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp), albeit with very low efficiency. The physiological substrate may be different. Displays neither proline racemase activity nor t3LHyp dehydratase activity. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.741 |
Csal_2340 | Csal_2339 | Csal_2340 | Csal_2339 | Alcohol dehydrogenase, zinc-binding protein. | Proline racemase; In vitro, catalyzes the epimerization of trans-4-hydroxy-L- proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp), albeit with very low efficiency. The physiological substrate may be different. Displays neither proline racemase activity nor t3LHyp dehydratase activity. | 0.936 |