node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arth_0225 | Arth_0226 | Arth_0225 | Arth_0226 | PDZ/DHR/GLGF domain protein; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: fra:Francci3_1988 peptidase S1 and S6, chymotrypsin/Hap. | Alpha-N-arabinofuranosidase; PFAM: alpha-L-arabinofuranosidase domain protein; KEGG: sma:SAV5743 putative alpha-L-arabinofuranosidase. | 0.505 |
Arth_0225 | Arth_2999 | Arth_0225 | Arth_2999 | PDZ/DHR/GLGF domain protein; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: fra:Francci3_1988 peptidase S1 and S6, chymotrypsin/Hap. | Putative signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; PspC domain protein; KEGG: sma:SAV3471 two-component system sensor kinase. | 0.523 |
Arth_0225 | arc | Arth_0225 | Arth_2173 | PDZ/DHR/GLGF domain protein; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: fra:Francci3_1988 peptidase S1 and S6, chymotrypsin/Hap. | Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.780 |
Arth_0225 | clpP | Arth_0225 | Arth_2404 | PDZ/DHR/GLGF domain protein; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: fra:Francci3_1988 peptidase S1 and S6, chymotrypsin/Hap. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.484 |
Arth_0225 | clpP-2 | Arth_0225 | Arth_2405 | PDZ/DHR/GLGF domain protein; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: fra:Francci3_1988 peptidase S1 and S6, chymotrypsin/Hap. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.488 |
Arth_0225 | def-2 | Arth_0225 | Arth_2193 | PDZ/DHR/GLGF domain protein; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: fra:Francci3_1988 peptidase S1 and S6, chymotrypsin/Hap. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.535 |
Arth_0225 | glpK | Arth_0225 | Arth_1803 | PDZ/DHR/GLGF domain protein; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: fra:Francci3_1988 peptidase S1 and S6, chymotrypsin/Hap. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.563 |
Arth_0225 | glpK-2 | Arth_0225 | Arth_2248 | PDZ/DHR/GLGF domain protein; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: fra:Francci3_1988 peptidase S1 and S6, chymotrypsin/Hap. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.563 |
Arth_0225 | rplT | Arth_0225 | Arth_1479 | PDZ/DHR/GLGF domain protein; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: fra:Francci3_1988 peptidase S1 and S6, chymotrypsin/Hap. | LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). | 0.493 |
Arth_0225 | rplY | Arth_0225 | Arth_1219 | PDZ/DHR/GLGF domain protein; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: fra:Francci3_1988 peptidase S1 and S6, chymotrypsin/Hap. | LSU ribosomal protein L25P; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.493 |
Arth_0226 | Arth_0225 | Arth_0226 | Arth_0225 | Alpha-N-arabinofuranosidase; PFAM: alpha-L-arabinofuranosidase domain protein; KEGG: sma:SAV5743 putative alpha-L-arabinofuranosidase. | PDZ/DHR/GLGF domain protein; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: fra:Francci3_1988 peptidase S1 and S6, chymotrypsin/Hap. | 0.505 |
Arth_2999 | Arth_0225 | Arth_2999 | Arth_0225 | Putative signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; PspC domain protein; KEGG: sma:SAV3471 two-component system sensor kinase. | PDZ/DHR/GLGF domain protein; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: fra:Francci3_1988 peptidase S1 and S6, chymotrypsin/Hap. | 0.523 |
arc | Arth_0225 | Arth_2173 | Arth_0225 | Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | PDZ/DHR/GLGF domain protein; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: fra:Francci3_1988 peptidase S1 and S6, chymotrypsin/Hap. | 0.780 |
arc | glpK | Arth_2173 | Arth_1803 | Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.919 |
arc | glpK-2 | Arth_2173 | Arth_2248 | Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.919 |
clpP | Arth_0225 | Arth_2404 | Arth_0225 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | PDZ/DHR/GLGF domain protein; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: fra:Francci3_1988 peptidase S1 and S6, chymotrypsin/Hap. | 0.484 |
clpP | clpP-2 | Arth_2404 | Arth_2405 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.998 |
clpP | def-2 | Arth_2404 | Arth_2193 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.737 |
clpP-2 | Arth_0225 | Arth_2405 | Arth_0225 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | PDZ/DHR/GLGF domain protein; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: fra:Francci3_1988 peptidase S1 and S6, chymotrypsin/Hap. | 0.488 |
clpP-2 | clpP | Arth_2405 | Arth_2404 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.998 |