STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arth_0781RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (319 aa)    
Predicted Functional Partners:
Arth_2072
Prolyl aminopeptidase 2, Serine peptidase, MEROPS family S33; PFAM: alpha/beta hydrolase fold; KEGG: sco:SCO0805 prolyl aminopeptidase.
 
      0.795
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
 
 0.714
Arth_0556
KEGG: gka:GK2478 hypothetical protein.
  
  
 0.705
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
 
 
 0.640
Arth_2420
TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: tws:TW367 single-strand DNA binding protein.
   
 
 0.635
Arth_4119
TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: nfa:nfa55730 putative single-strand binding protein.
   
 
 0.635
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
      0.617
Arth_2443
PFAM: protein of unknown function DUF164; KEGG: lxx:Lxx09950 hypothetical protein.
  
  
 0.603
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.570
Arth_2753
ATP-dependent DNA helicase, Rep family; PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: sco:SCO5188 putative ATP-dependent DNA helicase.
  
 
 0.544
Your Current Organism:
Arthrobacter sp. FB24
NCBI taxonomy Id: 290399
Other names: A. sp. FB24
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