node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arth_1454 | Arth_1569 | Arth_1454 | Arth_1569 | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: sma:SAV2510 putative FtsK; Belongs to the FtsK/SpoIIIE/SftA family. | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: lxx:Lxx15270 cell division protein; Belongs to the SEDS family. | 0.847 |
Arth_1454 | lexA | Arth_1454 | Arth_1468 | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: sma:SAV2510 putative FtsK; Belongs to the FtsK/SpoIIIE/SftA family. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.530 |
Arth_1454 | recA | Arth_1454 | Arth_1460 | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: sma:SAV2510 putative FtsK; Belongs to the FtsK/SpoIIIE/SftA family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.459 |
Arth_1469 | lexA | Arth_1469 | Arth_1468 | PFAM: Peptidoglycan-binding LysM; KEGG: lxx:Lxx15870 conserved ypothetical protein. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.617 |
Arth_1518 | lexA | Arth_1518 | Arth_1468 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.671 |
Arth_1518 | recA | Arth_1518 | Arth_1460 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.869 |
Arth_1518 | recF | Arth_1518 | Arth_0004 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.750 |
Arth_1569 | Arth_1454 | Arth_1569 | Arth_1454 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: lxx:Lxx15270 cell division protein; Belongs to the SEDS family. | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: sma:SAV2510 putative FtsK; Belongs to the FtsK/SpoIIIE/SftA family. | 0.847 |
Arth_1569 | Arth_2021 | Arth_1569 | Arth_2021 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: lxx:Lxx15270 cell division protein; Belongs to the SEDS family. | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: nfa:nfa56150 putative DNA polymerase IV family protein. | 0.611 |
Arth_1569 | Arth_3841 | Arth_1569 | Arth_3841 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: lxx:Lxx15270 cell division protein; Belongs to the SEDS family. | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: rfr:Rfer_4341 DNA-directed DNA polymerase. | 0.611 |
Arth_1569 | dinB | Arth_1569 | Arth_1559 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: lxx:Lxx15270 cell division protein; Belongs to the SEDS family. | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.660 |
Arth_1569 | lexA | Arth_1569 | Arth_1468 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: lxx:Lxx15270 cell division protein; Belongs to the SEDS family. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.528 |
Arth_2021 | Arth_1569 | Arth_2021 | Arth_1569 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: nfa:nfa56150 putative DNA polymerase IV family protein. | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: lxx:Lxx15270 cell division protein; Belongs to the SEDS family. | 0.611 |
Arth_2021 | lexA | Arth_2021 | Arth_1468 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: nfa:nfa56150 putative DNA polymerase IV family protein. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.760 |
Arth_2021 | recA | Arth_2021 | Arth_1460 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: nfa:nfa56150 putative DNA polymerase IV family protein. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.784 |
Arth_3841 | Arth_1569 | Arth_3841 | Arth_1569 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: rfr:Rfer_4341 DNA-directed DNA polymerase. | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: lxx:Lxx15270 cell division protein; Belongs to the SEDS family. | 0.611 |
Arth_3841 | lexA | Arth_3841 | Arth_1468 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: rfr:Rfer_4341 DNA-directed DNA polymerase. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.775 |
Arth_3841 | recA | Arth_3841 | Arth_1460 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: rfr:Rfer_4341 DNA-directed DNA polymerase. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.784 |
argR | lexA | Arth_1501 | Arth_1468 | Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.552 |
dinB | Arth_1569 | Arth_1559 | Arth_1569 | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: lxx:Lxx15270 cell division protein; Belongs to the SEDS family. | 0.660 |