node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arth_1423 | argG | Arth_1423 | Arth_1502 | PFAM: aminotransferase, class I and II; KEGG: mth:MTH1894 aspartate aminotransferase homolog. | PFAM: argininosuccinate synthase; KEGG: sma:SAV6778 putative argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.923 |
Arth_1423 | argJ | Arth_1423 | Arth_1497 | PFAM: aminotransferase, class I and II; KEGG: mth:MTH1894 aspartate aminotransferase homolog. | Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.910 |
Arth_1423 | purA | Arth_1423 | Arth_0522 | PFAM: aminotransferase, class I and II; KEGG: mth:MTH1894 aspartate aminotransferase homolog. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.916 |
argB | argC | Arth_1498 | Arth_1496 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.999 |
argB | argD | Arth_1498 | Arth_1499 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class-III; KEGG: nfa:nfa19390 putative acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.994 |
argB | argF | Arth_1498 | Arth_1500 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.995 |
argB | argG | Arth_1498 | Arth_1502 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | PFAM: argininosuccinate synthase; KEGG: sma:SAV6778 putative argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.990 |
argB | argH | Arth_1498 | Arth_1503 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: tfu:Tfu_2051 argininosuccinate lyase. | 0.993 |
argB | argJ | Arth_1498 | Arth_1497 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.999 |
argB | argR | Arth_1498 | Arth_1501 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes. | 0.995 |
argB | carB | Arth_1498 | Arth_2262 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: sco:SCO1483 carbamoylphosphate synthetase large chain. | 0.714 |
argC | argB | Arth_1496 | Arth_1498 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.999 |
argC | argD | Arth_1496 | Arth_1499 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class-III; KEGG: nfa:nfa19390 putative acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.999 |
argC | argF | Arth_1496 | Arth_1500 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.990 |
argC | argG | Arth_1496 | Arth_1502 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | PFAM: argininosuccinate synthase; KEGG: sma:SAV6778 putative argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.990 |
argC | argH | Arth_1496 | Arth_1503 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: tfu:Tfu_2051 argininosuccinate lyase. | 0.992 |
argC | argJ | Arth_1496 | Arth_1497 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.998 |
argC | argR | Arth_1496 | Arth_1501 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes. | 0.992 |
argC | carB | Arth_1496 | Arth_2262 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: sco:SCO1483 carbamoylphosphate synthetase large chain. | 0.707 |
argD | argB | Arth_1499 | Arth_1498 | TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class-III; KEGG: nfa:nfa19390 putative acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.994 |