STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (345 aa)    
Predicted Functional Partners:
Arth_2771
TIGRFAM: protoporphyrinogen oxidase; PFAM: FAD dependent oxidoreductase; KEGG: lxx:Lxx01060 protoporphyrinogen oxidase.
 
 
 0.998
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.986
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.978
Arth_2766
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
 
 0.962
Arth_3111
TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: tfu:Tfu_2221 uroporphyrin-III C-methyltransferase, C-terminal:siroheme synthase, N-terminal.
    
 0.961
Arth_1256
PFAM: transcriptional regulator domain protein; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO2958 uroporphyrinogen-III synthetase.
  
 
 0.946
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.934
hemL
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: lxx:Lxx01130 glutamate-1-semialdehyde 2,1-aminomutase.
 
  
 0.921
Arth_1257
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mma:MM0307 uroporphyrin-III C-methyltransferase.
    
 0.917
Arth_2765
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sco:SCO3311 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.914
Your Current Organism:
Arthrobacter sp. FB24
NCBI taxonomy Id: 290399
Other names: A. sp. FB24
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