node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arth_0593 | Arth_2392 | Arth_0593 | Arth_2392 | PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: pac:PPA1712 putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Phosphomethylpyrimidine kinase; KEGG: cef:CE1591 putative thiamin biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: TENA/THI-4 domain protein; Phosphomethylpyrimidine kinase type-1. | 0.880 |
Arth_0593 | Arth_2774 | Arth_0593 | Arth_2774 | PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: pac:PPA1712 putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: tfu:Tfu_0520 rhodanese-like protein. | 0.695 |
Arth_0593 | Arth_2780 | Arth_0593 | Arth_2780 | PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: pac:PPA1712 putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: sma:SAV6094 thiamine biosynthesis ThiS. | 0.732 |
Arth_0593 | Arth_2781 | Arth_0593 | Arth_2781 | PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: pac:PPA1712 putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; KEGG: pac:PPA0520 FAD dependent oxidoreductase. | 0.650 |
Arth_0593 | thiC | Arth_0593 | Arth_2487 | PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: pac:PPA1712 putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.779 |
Arth_0593 | thiE | Arth_0593 | Arth_2782 | PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: pac:PPA1712 putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.970 |
Arth_0593 | thiG | Arth_0593 | Arth_2779 | PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: pac:PPA1712 putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.878 |
Arth_0593 | thiL | Arth_0593 | Arth_2512 | PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: pac:PPA1712 putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.556 |
Arth_2392 | Arth_0593 | Arth_2392 | Arth_0593 | Phosphomethylpyrimidine kinase; KEGG: cef:CE1591 putative thiamin biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: TENA/THI-4 domain protein; Phosphomethylpyrimidine kinase type-1. | PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: pac:PPA1712 putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.880 |
Arth_2392 | Arth_2774 | Arth_2392 | Arth_2774 | Phosphomethylpyrimidine kinase; KEGG: cef:CE1591 putative thiamin biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: TENA/THI-4 domain protein; Phosphomethylpyrimidine kinase type-1. | PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: tfu:Tfu_0520 rhodanese-like protein. | 0.901 |
Arth_2392 | Arth_2780 | Arth_2392 | Arth_2780 | Phosphomethylpyrimidine kinase; KEGG: cef:CE1591 putative thiamin biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: TENA/THI-4 domain protein; Phosphomethylpyrimidine kinase type-1. | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: sma:SAV6094 thiamine biosynthesis ThiS. | 0.956 |
Arth_2392 | Arth_2781 | Arth_2392 | Arth_2781 | Phosphomethylpyrimidine kinase; KEGG: cef:CE1591 putative thiamin biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: TENA/THI-4 domain protein; Phosphomethylpyrimidine kinase type-1. | TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; KEGG: pac:PPA0520 FAD dependent oxidoreductase. | 0.687 |
Arth_2392 | thiC | Arth_2392 | Arth_2487 | Phosphomethylpyrimidine kinase; KEGG: cef:CE1591 putative thiamin biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: TENA/THI-4 domain protein; Phosphomethylpyrimidine kinase type-1. | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.997 |
Arth_2392 | thiE | Arth_2392 | Arth_2782 | Phosphomethylpyrimidine kinase; KEGG: cef:CE1591 putative thiamin biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: TENA/THI-4 domain protein; Phosphomethylpyrimidine kinase type-1. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |
Arth_2392 | thiG | Arth_2392 | Arth_2779 | Phosphomethylpyrimidine kinase; KEGG: cef:CE1591 putative thiamin biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: TENA/THI-4 domain protein; Phosphomethylpyrimidine kinase type-1. | Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.985 |
Arth_2392 | thiL | Arth_2392 | Arth_2512 | Phosphomethylpyrimidine kinase; KEGG: cef:CE1591 putative thiamin biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: TENA/THI-4 domain protein; Phosphomethylpyrimidine kinase type-1. | Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.543 |
Arth_2774 | Arth_0593 | Arth_2774 | Arth_0593 | PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: tfu:Tfu_0520 rhodanese-like protein. | PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: pac:PPA1712 putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.695 |
Arth_2774 | Arth_2392 | Arth_2774 | Arth_2392 | PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: tfu:Tfu_0520 rhodanese-like protein. | Phosphomethylpyrimidine kinase; KEGG: cef:CE1591 putative thiamin biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: TENA/THI-4 domain protein; Phosphomethylpyrimidine kinase type-1. | 0.901 |
Arth_2774 | Arth_2780 | Arth_2774 | Arth_2780 | PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: tfu:Tfu_0520 rhodanese-like protein. | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: sma:SAV6094 thiamine biosynthesis ThiS. | 0.868 |
Arth_2774 | Arth_2781 | Arth_2774 | Arth_2781 | PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: tfu:Tfu_0520 rhodanese-like protein. | TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; KEGG: pac:PPA0520 FAD dependent oxidoreductase. | 0.469 |