node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arth_3447 | clpP | Arth_3447 | Arth_2404 | PFAM: heat shock protein DnaJ domain protein; KEGG: sma:SAV7239 putative heat shock protein DnaJ. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.427 |
Arth_3447 | clpP-2 | Arth_3447 | Arth_2405 | PFAM: heat shock protein DnaJ domain protein; KEGG: sma:SAV7239 putative heat shock protein DnaJ. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.421 |
Arth_3447 | dnaK | Arth_3447 | Arth_3808 | PFAM: heat shock protein DnaJ domain protein; KEGG: sma:SAV7239 putative heat shock protein DnaJ. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.957 |
Arth_3447 | groL1 | Arth_3447 | Arth_0779 | PFAM: heat shock protein DnaJ domain protein; KEGG: sma:SAV7239 putative heat shock protein DnaJ. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.693 |
Arth_3447 | groL2 | Arth_3447 | Arth_2886 | PFAM: heat shock protein DnaJ domain protein; KEGG: sma:SAV7239 putative heat shock protein DnaJ. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.693 |
Arth_3447 | groS | Arth_3447 | Arth_2887 | PFAM: heat shock protein DnaJ domain protein; KEGG: sma:SAV7239 putative heat shock protein DnaJ. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.689 |
Arth_3447 | grpE | Arth_3447 | Arth_3807 | PFAM: heat shock protein DnaJ domain protein; KEGG: sma:SAV7239 putative heat shock protein DnaJ. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.889 |
Arth_3447 | hrcA | Arth_3447 | Arth_2236 | PFAM: heat shock protein DnaJ domain protein; KEGG: sma:SAV7239 putative heat shock protein DnaJ. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.708 |
Arth_3806 | clpP | Arth_3806 | Arth_2404 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: lxx:Lxx23760 DnaJ protein. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.427 |
Arth_3806 | clpP-2 | Arth_3806 | Arth_2405 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: lxx:Lxx23760 DnaJ protein. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.421 |
Arth_3806 | dnaK | Arth_3806 | Arth_3808 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: lxx:Lxx23760 DnaJ protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.997 |
Arth_3806 | groL1 | Arth_3806 | Arth_0779 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: lxx:Lxx23760 DnaJ protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.745 |
Arth_3806 | groL2 | Arth_3806 | Arth_2886 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: lxx:Lxx23760 DnaJ protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.744 |
Arth_3806 | groS | Arth_3806 | Arth_2887 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: lxx:Lxx23760 DnaJ protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.689 |
Arth_3806 | grpE | Arth_3806 | Arth_3807 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: lxx:Lxx23760 DnaJ protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.971 |
Arth_3806 | hrcA | Arth_3806 | Arth_2236 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: lxx:Lxx23760 DnaJ protein. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.708 |
clpP | Arth_3447 | Arth_2404 | Arth_3447 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | PFAM: heat shock protein DnaJ domain protein; KEGG: sma:SAV7239 putative heat shock protein DnaJ. | 0.427 |
clpP | Arth_3806 | Arth_2404 | Arth_3806 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: lxx:Lxx23760 DnaJ protein. | 0.427 |
clpP | clpP-2 | Arth_2404 | Arth_2405 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.998 |
clpP | dnaJ | Arth_2404 | Arth_2235 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.427 |