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obg protein (Clostridium beijerinckii) - STRING interaction network
"obg" - GTPase Obg in Clostridium beijerinckii
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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obgGTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family (430 aa)    
Predicted Functional Partners:
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20 (103 aa)
 
  0.985
rpmA
PFAM- ribosomal protein L27; KEGG- cpr-CPR_2095 ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family (99 aa)
 
  0.963
lepA
Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (603 aa)
 
   
  0.936
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (144 aa)
 
 
  0.911
ruvB
Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (347 aa)
 
        0.908
rplD
50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5’-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (206 aa)
   
 
  0.903
rplQ
PFAM- ribosomal protein L17; KEGG- cpr-CPR_2369 ribosomal protein L17 (113 aa)
   
 
  0.886
Cbei_0516
Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil (299 aa)
 
 
  0.885
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (119 aa)
 
 
  0.875
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (695 aa)
 
 
  0.875
Your Current Organism:
Clostridium beijerinckii
NCBI taxonomy Id: 290402
Other names: C. beijerinckii NCIMB 8052, Clostridium [acetobutylicum] NCIMB 8052, Clostridium beijerinckii, Clostridium beijerinckii NCIMB 8052, Clostridium beijerinckii str. NCIMB 8052, Clostridium beijerinckii strain NCIMB 8052
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