node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Paes_0103 | Paes_2188 | Paes_0103 | Paes_2188 | KEGG: cph:Cpha266_1423 hypothetical protein. | PFAM: protein of unknown function DUF452; KEGG: cph:Cpha266_0114 protein of unknown function DUF452. | 0.463 |
Paes_0103 | bioC | Paes_0103 | Paes_2187 | KEGG: cph:Cpha266_1423 hypothetical protein. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.438 |
Paes_0173 | bioC | Paes_0173 | Paes_2187 | 3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.900 |
Paes_0173 | birA | Paes_0173 | Paes_2191 | 3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.706 |
Paes_2188 | Paes_0103 | Paes_2188 | Paes_0103 | PFAM: protein of unknown function DUF452; KEGG: cph:Cpha266_0114 protein of unknown function DUF452. | KEGG: cph:Cpha266_1423 hypothetical protein. | 0.463 |
Paes_2188 | Paes_2189 | Paes_2188 | Paes_2189 | PFAM: protein of unknown function DUF452; KEGG: cph:Cpha266_0114 protein of unknown function DUF452. | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; KEGG: cph:Cpha266_0113 8-amino-7-oxononanoate synthase. | 0.987 |
Paes_2188 | Paes_2192 | Paes_2188 | Paes_2192 | PFAM: protein of unknown function DUF452; KEGG: cph:Cpha266_0114 protein of unknown function DUF452. | Hypothetical protein. | 0.413 |
Paes_2188 | bioA | Paes_2188 | Paes_2185 | PFAM: protein of unknown function DUF452; KEGG: cph:Cpha266_0114 protein of unknown function DUF452. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.813 |
Paes_2188 | bioB | Paes_2188 | Paes_2190 | PFAM: protein of unknown function DUF452; KEGG: cph:Cpha266_0114 protein of unknown function DUF452. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.881 |
Paes_2188 | bioC | Paes_2188 | Paes_2187 | PFAM: protein of unknown function DUF452; KEGG: cph:Cpha266_0114 protein of unknown function DUF452. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.976 |
Paes_2188 | bioD | Paes_2188 | Paes_2186 | PFAM: protein of unknown function DUF452; KEGG: cph:Cpha266_0114 protein of unknown function DUF452. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.918 |
Paes_2188 | birA | Paes_2188 | Paes_2191 | PFAM: protein of unknown function DUF452; KEGG: cph:Cpha266_0114 protein of unknown function DUF452. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.743 |
Paes_2189 | Paes_2188 | Paes_2189 | Paes_2188 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; KEGG: cph:Cpha266_0113 8-amino-7-oxononanoate synthase. | PFAM: protein of unknown function DUF452; KEGG: cph:Cpha266_0114 protein of unknown function DUF452. | 0.987 |
Paes_2189 | Paes_2192 | Paes_2189 | Paes_2192 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; KEGG: cph:Cpha266_0113 8-amino-7-oxononanoate synthase. | Hypothetical protein. | 0.413 |
Paes_2189 | bioA | Paes_2189 | Paes_2185 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; KEGG: cph:Cpha266_0113 8-amino-7-oxononanoate synthase. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.988 |
Paes_2189 | bioB | Paes_2189 | Paes_2190 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; KEGG: cph:Cpha266_0113 8-amino-7-oxononanoate synthase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.947 |
Paes_2189 | bioC | Paes_2189 | Paes_2187 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; KEGG: cph:Cpha266_0113 8-amino-7-oxononanoate synthase. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.913 |
Paes_2189 | bioD | Paes_2189 | Paes_2186 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; KEGG: cph:Cpha266_0113 8-amino-7-oxononanoate synthase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.968 |
Paes_2189 | birA | Paes_2189 | Paes_2191 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; KEGG: cph:Cpha266_0113 8-amino-7-oxononanoate synthase. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.832 |
Paes_2192 | Paes_2188 | Paes_2192 | Paes_2188 | Hypothetical protein. | PFAM: protein of unknown function DUF452; KEGG: cph:Cpha266_0114 protein of unknown function DUF452. | 0.413 |